1. CyberKnife®: Tumor Removal
Jeremy Galle
BME 281
November 21st 2012

2. CyberKnife® Developed by Accuray Linear Accelerator (LINAC) machine
Uses microwave technology to generate photons
Weightless elementary particle
Used in Stereotactic Radiosurgery
Non-invasive form of radiation therapy
Relies on:
CT scan
Determine location, size, shape of tumor
Radiation
Tumor DNA mutations
Image-guided radiation therapy (IGRT)
Computer-controlled robotic arm
Custom treatment plan

3. Results January 2012 – 160 person case study conducted
The People’s Liberation Army 107th Hospital in China
18 people had their tumors disappear
99 exhibited tumor shrinkage
35 were unaffected
8 had tumor growth
Conclusion: 73.13% effectiveness

4. Advantages/Disadvantages
Non-invasive
No recovery time
Can treat tumors anywhere in body
Extremely accurate (within 0.5mm of target)
Insurance can cover the costs
Minimal to no side effects
Disadvantages:
Not always effective
Expensive without insurance ($12,000 for one treatment)
Results take time
More than one treatment may be necessary
Procedure is longer than comparable treatments (60-90 mins)

5. Future of the technology
More effective
No patients with reverse trends
More accurate
No surrounding tissue damage
No side effects
Quicker results
Less expensive
Quicker procedure times
More flexible treatment plans

6. Works Cited
Chen, Viola, Eric Oermann, Saloomeh Vahdat, Jennifer Riben, Simeng Suy, Xia Yu, Sean Collins, and Brian Collins. "CyberKnife with Tumor Tracking: An Effective Treatment for High- Risk Surgical Patients with Stage I Non-Small Cell Lung Cancer." Frontiers in Oncology 2.9 (2012): n. pag. PubMed. Web. 18 Nov < PMC />.
CyberKnife. Accuray, n.d. Web. 18 Nov <
CyberKnife® at Pennsylvania Hospital." Penn Medicine. N.p., n.d. Web. 18 Nov <
"Cyberknife.” Wikipedia. Wikimedia Foundation, 11 Dec Web. 18 Nov < en.wikipedia.org/wiki/Cyberknife>.
Vesper, J., E Bolke, C. Wille, P. A. Gerber, C. Matuschek, and M. Peiper. "Current Concepts in Stereotactic Radiosurgery - a Neurosurgical and Radiooncological Point of View." European Journal of Medical Research 14.3 (2009): n. pag. PubMed. Web. 18 Nov <
Wang, Yi-Shan, Yuan-Yuan Wang, Peng Jiang, Jian-Jun Ma, Zhen Qu, Xi-Lin Wang, Jun-Ti Li, and Xi- Feng Jia. "Short-term Outcomes of CyberKnife Therapy for Advanced High-risk Tumors: A Report of 160 Cases." PubMed Central. NCBI, 12 Jan Web. 18 Nov <