2. 2006-2007 Genetics Why do we look the way we do?

3. 2007-2008 Genetics & The Work of Mendel

4. Modern genetics began in the mid- 1800s in an abbey garden, where a monk named Gregor Mendel documented inheritance in peas – used good experimental design – used mathematical analysis collected data & counted them – excellent example of scientific method Gregor Mendel

5. Pollen transferred from white flower to stigma of purple flower all purple flowers result Mendel’s work ? self-pollinate Bred pea plants – cross-pollinate true breeding parents – planted seeds & then observed traits – allowed offspring to self-pollinate & observed next generation

6. Mendel collected data for 7 pea traits

7. 2 nd generation 3:1 75% purple-flower peas 25% white-flower peas Looking closer at Mendel’s work Parents 100% 1 st generation (hybrids) 100% purple-flower peas X true-breeding purple-flower peas true-breeding white-flower peas self-pollinate

8. 2 nd generation 3:1 75% purple-flower peas 25% white-flower peas Looking closer at Mendel’s work Parents 100% 1 st generation (hybrids) 100% purple-flower peas X true-breeding purple-flower peas true-breeding white-flower peas self-pollinate

9. What did Mendel’s findings mean? Some traits mask others – purple & white flower colors are separate traits that do not blend purple x white ≠ light purple purple masked white – dominant allele functional protein – affects characteristic masks other alleles – recessive allele no noticeable effect allele makes a non-functioning protein homologous chromosomes I’ll speak for both of us! allele producing functional protein allele producing nonfunctioning protein

10. Genotype vs. phenotype Difference between how an organism “looks” & its genetics – phenotype description of an organism’s trait – genotype description of an organism’s genetic makeup Explain Mendel’s results using …dominant & recessive …phenotype & genotype F1F1 P X purplewhite all purple

11. Making crosses Can represent alleles as letters – flower color alleles  P or p – true-breeding purple-flower peas  PP (homozygous dominant) “same zygote” – true-breeding white-flower peas  pp (homozygous recessive) – hybrid purple flower peas  Pp (heterozygous) “different zygote” PP x pp PpPp F1F1 P X purplewhite all purple

12. R – dominant allele (tongue roller) Is Rr homozygous or heterozygous? Heterozygous B – dominant allele (baldness) Is bb homozygous or heterozygous? Homozygous F – dominant allele (freckles) Is FF homozygous or heterozygous? Homozygous

13. Punnett squares Pp x Pp Pp male / sperm P p female / eggs PP 75% 25% 3:1 25% 50% 25% 1:2:1 % genotype % phenotype PPPpPp PpPppp PpPp PpPp 1 st generation (hybrids) Aaaaah, phenotype & genotype can have different ratios

14. 2007-2008 Write a two sentence summary comparing phenotype & genotype As well as heterozygous & homozygous