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Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465.

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Presentation on theme: "Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465."— Presentation transcript:

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2 Three-component coupling reactions in ionic liquids: a facile synthesis of a-aminonitriles New J. Chem., 2003, 27, 462–465

3 Recycle 6 times without any apparent loss of activity

4 Montmorillonite KSF clay catalyzed one-pot synthesis of a-aminonitriles Tetrahedron 60 (2004) 1767–1771

5 solid acids recycle 1. 92 % 2. 87 % 3. 82 %

6 Nickel(II) chloride catalyzed one-pot synthesis of - aminonitriles Journal of Molecular Catalysis A: Chemical 225 (2005) 169–171

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9 Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs PNAS March 6, 2007 vol. 104 no. 10

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12 Fe(Cp) 2 PF 6 catalyzed efficient Strecker reactions of ketones and aldehydes under solvent-free conditions Tetrahedron Letters 49 (2008) 640–644

13 1 : 1 : 1.3

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