1. SciFinder Scholar Gary Wiggins wiggins@indiana.edu IU School of Informatics

2. SciFinder and SciFinder Scholar Includes access to the CA, Registry, CHEMCATS, CHEMLIST files, plus Medline (1958-) Easy structure searching capabilities Integrated with ChemPort for easy access to the primary literature Download page for SFS: http://www.indiana.edu/~libchem/protected/sciintro.html Don’t forget the site.prf file!

3. SciFinder Scholar: IU Options 24-Hour Access Full Substructure Searching Seven Simultaneous Users License serves all 8 IU campuses

4. SciFinder Scholar Databases Chemical Abstracts Service Databases on SFS CAPlus, 1907- Registry File, 1907- CASREACT, 1907- CHEMCATS CHEMLIST National Library of Medicine Database MEDLINE, 1958-

5. SciFinder Scholar Content CAPlus Over 26,000,000 documents as of 12/31/2003 Covers all areas of chemistry: journal articles from more than 8000 journals Enhanced coverage for 1500 journals since 1994 patents conference proceedings books, dissertations, and technical reports Other types of literature

6. Relative Contributions of Literature Types to CA Used with the permission of Chemical Abstracts Service (CAS), a division of the American Chemical Society, from: http://www.cas.org/casdb.html

7. SciFinder Scholar Content MEDLINE Over 13 million articles as of 4/3/2003 More than 3900 journals Searched simultaneously with CAPlus Unless turned off: Results in duplicate answers

8. CAPlus/MEDLINE Search Options

9. CAS DBs: Registry File “Authority” file that lets indexers and searchers definitively identify a substance as new or find a previous entry Contains all types of chemical substances, including biomolecules Best file for chemical names Many physical properties being added Linked to CA and other files through the Registry Number (RN)

10. Registry File Contents Includes synonyms, molecular formulas, alloy composition tables, classes for polymers, nucleic acid and protein sequences, ring analysis data, and structure diagrams Also: experimental and calculated property data from various sources as well as super roles and document type information from CAplus

11. Size of the Registry File DateSunday, 9/26/2004 Count24,205,177 organic and inorganic substances 48,092,380 sequences CAS Registry Number751481-24-0 is the most recent CAS Registry Number

12. Registry File Enhancements Calculated property values Number of hydrogen donors Number of hydrogen acceptors Number of rotatable bonds Molecular weight LogD, logP, pKa Solubility in water Experimental physical properties Only from 1975-1991

13. Chemical Substance Search

14. CAS DBs: CASReact Derived from journal and patent documents from 1840 to date Contains both single-step and multistep reactions Structure searchable for reagents, reactants, and products Contains yield data, reaction conditions, etc. Common functional groups are searchable

15. CHEMLIST and CHEMCATS Both available in SciFinder Scholar CHEMLIST: Regulated chemicals listing Chemical substances on national inventories Good for foreign language chemical names CHEMCATS: commercially available chemicals Includes worldwide suppliers Links for both included on the Substance Search results record

16. CAS Databases: Other MARPAT--more than 500,000 Markush structure records for patents found in the CA File with patent publication year 1988 to the present TOXCENTER--covers the pharmacological, biochemical, physiological, and toxicological effects of drugs and other chemicals

17. CAS Roles Used in conjunction with chemical substance searches Seven super roles, e.g., ANST, BIOL, CMBI, FORM, OCCU, PREP, PROC, RACT, USES Over 60 more specific role descriptors, e.g., with PREP: BMF Bioindustrial manufacture BPN Biosynthetic preparation BYP Byproduct Combinatorial preparation IMF Industrial manufacture PNU Preparation, unclassified PUR Purification or recovery SPN Synthetic preparation Also two roles not up-posted to super roles: PRP (Properties) and MSC (Miscellaneous)