1. Copyright© 2010 Continua Health Alliance ® All Rights Reserved The Next Generation of Healthcare: Personal Connected Health & Wellness www.continuaalliance.org

2. | Mission “Our Mission is to establish an ecosystem of interoperable personal connected health systems that empower individuals and organizations to better manage their health and wellness”

3. | The Continuum of Care CONTINUUM of LIFE CONTINUUM of CAREGIVERS Infant Amateur Athlete Diet/Fitness Focused Active Lifestyle Living Independently Chronic Patient AcuteRecovery Physician HomeHealthcareProfessional Wellness Coach Family Caregivers Extended Family Continua Health Alliance enables a personal connected health eco-system that empowers individuals & families to better manage their own health and wellness across the continuum of life and care methods.

4. | 4 Goal: Realize Peak Health Potential Goal –Experience peak health potential throughout life for a high quality of life at minimal costs Reality –Average individual is experiencing much less of full health potential than expected at a high financial & quality of life cost Cause –Adverse health events such as stress, poor nutrition, inactivity… are causing the population to fall away from their peak health potential Adapted from Oregon Medical Labs 0 25 65 Age Illness Pre-Illness Wellness Unpredictable Health Predictable (Rules-based) Health Death 60-80% Lifestyle Management Modifiable lifestyle Irreversible Disease state Happening earlier in life Higher $$ Costs to All Realize Peak Health Potential

5. | The Challenge Worldwide today: –1 billion adults overweight –860 million individuals with chronic conditions –600 million individuals age 60 or older –75-85% of healthcare spending is on chronic condition management Source: World Health Organization; McKinsey

6. | The Goal: Improve Lifestyle Choices, Health = Non Modifiable Contributors to Disease = Modifiable Contributors to Disease Hu et al. Diet, lifestyle and the risk of type 2 Diabetes in women. NEJM 2001 Sep 13;345(11):790-7. Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willett WC. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med. 2000; 343: 16–22

7. | The Solution: Personal Connected Healthcare There is increasing evidence to support the value of remote monitoring for individuals with chronic conditions, including: 35-56% reduction in mortality; 47% reduction in risk of hospitalization; 6 days reduction in length of hospital admission and 65% reduction in office visits; 40-64% reduction in physician time for checks and 63% reduction in transport costs (Cleland et al 2005; Lee R, Goldberg et al, 2003; Scalvini S et al., 2001; Elsner et al, 2006; Van Ginneken et al 2006)

8. | Continua Domains To organize its work, Continua segmented the market in three large Domains Living Independently Longer Wellness Manage Chronic Conditions People are at the center of everything we do

9. | Wellness One billion adults overweight worldwide Internet Pedometer Blood-pressure Cuff Heart Strap Medication Tracking Weight Scale Fitness Equipment Digital Home Cell Phone PC Personal Health Record Healthcare Professionals Weight loss and fitness coaching Continua member companies help individuals live healthier, more active lives by connecting them to their wellness team through a more efficient exchange of personal fitness information.

10. | Internet Manage Chronic Conditions 860 million individuals with chronic conditions world wide Continua member companies help individuals with chronic conditions live healthier lives by connecting them to their care team through a more efficient exchange of personal health information. Pedometer Blood-pressure Cuff Pulse Ox Medication Tracking Weight Scale Fitness Equipment Digital Home Cell Phone Personal Health System PC Family Care Givers Disease Management Service Personal Health Record Healthcare Provider Thermometer Glucose Meter

11. | Internet Living Independently Longer 600 million elderly individuals world wide Continua member companies help the elderly live independently longer, with dignity and security, through the efficient exchange of personal health and safety information that connects them to their family and care team. Family Care Givers Elderly Monitoring Services Disease Management Service, Healthcare Provider Diet and Wellness Services Digital Home Pedometer Blood-pressure Cuff Medication Tracking Home Automation & Control Fitness Equipment Pulse Ox Cell Phone Personal Health System PC

12. | Already Complete: Interfaces & Standards Health Record Network Interface Personal Device Weight Scale Pulse Oximeter Independent Living Activity Cardio / Strength Medication Adherence Glucose Meter Pulse / Blood Pressure Thermometer Physical Activity Peak Flow Aggregation Manager Device Connectivity Wide Area Network (WAN) Interface Telehealth Service Center Health Records EHR PHR HIE NHIN CCD PCD 01 12 Continua BT Profiles

13. | Guidelines  Certification  Recognizable Logo Guidelines Continua member companies will select connectivity standards and publish Guidelines for strict interoperability. Certification and Logo Continua is establishing a test and certification program with a recognizable logo signifying the promise of interoperability with other certified products.

14. |  Plugfests participation  Participation in RFP MatchMaker program  Unlimited participation in Continua quarterly summits, town hall meetings, and education seminars  Access to market research data  Access to pre-publication drafts of the design guidelines  Internal and external education and training  Test and certification tools  Right to use certified logo upon completion of successful certification  Web-based environment (repository, collaboration tools)  Reference source code Ecosystem Development Developer Resources Market IntelligenceCollaboration Certification 14

15. | Board Members Continua Health Alliance Confidential 15 5/20/2015

16. | Promoter Members Open International Continua Health Alliance Confidential 16 5/20/2015

17. | Over 200 Member Companies! Contributors  Alive Inc.  Allion Labs, Inc.  ALPS Electric Co., Ltd.  ALPWISE  Amgen, Inc.  AstraZeneca  AT&T  AT4 Wireless  Austrian Institute of Technology GmbH  Bayer  Becton Dickinson  Biosense Technologies Pvt. Ltd.  Bluegiga Technologies Oy  BodyTel Europe GmbH  Brunel University  CapsuleTech, Inc.  CASIO Computer Co., Ltd.  CEA-LETI  Centre for Global eHealth Innovation  China Mobile Communications Co., Ltd. Research Institute  Christus Health  Cisco Systems, Inc.  Cnet Sweden  Cogent Healthcare Systems  CONNECTEDHEALTH PTE LTD.  CORE Corporation Chubu Company  Covidien  CSC  Dai Nippon Printing Co., Ltd.  DELTA  Denso International America, Inc.  Digi International  Doro AB  Dynastream Innovations Inc.  Elbrys Networks  Eli Lily and Company  empirica GmbH  Epstein, Becker, & Green, P.C. Flextronics Design SRL FORUS Health Pvt. Ltd. Fraunhofer Gesellschaft e.V. - Allianz AAL  Freescale Semiconductor  GE Healthcare  Gemalto M2M GmbH  Grid2Home  H3System Co., Ltd.  Health Insight Solutions GmbH  Healthrageous  Hitachi, Ltd.  Hospital Clinic  Huawei Technologies Co., Ltd.  Humana, Inc.  ICAR-CNR  Impact Health LLC  Industrial Technology Research Institute  Info Solution SpA  ISIRONA LLC  Kaiser Permanente  KDDI R&D Labs  Lamprey Networks, Inc.  LG Electronics Inc.  LifeWatch  Lyse Smart AS Maxim Integrated Products, Inc.

18. | Over 200 Member Companies! Contributors  MEDCOM - The Danish Healthcare Data Network  Medtronic  Medvivo Group Limited  Micro Market eHealth Solutions LLC.  Microchip Technology  MindTree Ltd.  MIR - Medical International Research  MITRE Corporation  MOH Holdings Pte. Ltd.  Murata Manufacturing Co., Ltd.  MyDoc Pte. Ltd.  National Library of Medicine  Navigant Consulting Inc.  NCI Technology Inc.  Neusoft Xikang Healthcare Technology Co., Ltd.  NHS Connecting for Health  Nihon Kohden Corporation  Nippon Telegraph and Telephone Corporation  Nokia Corporation  Nordic Semiconductor ASA  Novo Nordisk  Oki Electric Industry Co., Ltd.  ON Semiconductor  openit, Inc.  Oregon Scientific Inc.  PA Consulting Group  Polymap Wireless  Primum Health IT S.L.  Proskauer Rose LLP  Renesas Technology America  ResMed Corp.  Robert Bosch Healthcare Systems, Inc.  RTX A/S  Ryoyo Electro Corporation  S Global Holdings Pte. Ltd.  S3 Group  Sagentia Ltd.  Sanofi-Aventis  Seers Technology Co., Ltd.  Seiko Epson Corporation  SGS Group  SHL Telemedicine  Signove Tecnologia S.A.  SINTEF  Star Product Limited  Stollmann E+V GmbH  Stonestreet One, LLC  Sumitomo Electric Networks, Inc.  Sun-Tech Medical, Inc.  T-Systems International GmbH  TaiDoc Technology Corporation  TechMahindra  Telbios, SpA  Telecommunication Metrology Center of MIIT  TELUS Health Solutions  Terumo Corporation  The Scottish Centre for Telehealth  Tokyo Electron Device Ltd.  Toshiba Corporation  Trackmybeat Healthcare (India) Pvt. Ltd.  TTA  Tunstall  Tynetec Ltd.  UCB SA  UL  Unicare Saude  V.A.  Vigil Monitoring Ltd.  Vivify Health, Inc.  Vodafone Group Services Ltd.  Voluntis  Weinmann Geräte Für Medizin GmbH & Co. KG  Wind River

19. | Supporting Participants Continua Health Alliance Confidential 5/20/2015 19

20. | Industry Liaisons Continua Health Alliance Confidential 20 5/20/2015

21. | Building Awareness Around the World… Continua sponsored public symposiums and member summits Belfast 2010 2012: Austin, Berlin 2013: Portland, Edinburgh, Taipei London 2007 San Francisco June 2006, 2007, 2008 Boston October 2006, 2007, 2008, 2009 Ireland January 2008 February 2009 Spain March 2009 Tokyo April 2007 Vancouver June 2009 San Diego February 2010 South Korea 2010 Amsterdam 2011 Singapore 2011 Washington D.C. 2011 Austin 2012 Luxembourg April 2008

22. Thank you! For more information or to join Continua Health Alliance… Sign up for our newsletter admin@continuaalliance.org Visit our website www.continuaalliance.org admin@continuaalliance.org www.continuaalliance.org