1. Chapter 10 Lecture Mark D. Herbst, M.D., Ph.D.

3. Image Detail and Noise Two image characteristics that reduce the visibility of anatomy/pathology –Blurring – level of detail – related to pixel size –Visual Noise – random bright and dark dots These two are related, because if you improve one, you worsen the other.

7. Other image characteristics also impact visibility of anatomy/pathology Camouflage Irregular borders Low contrast Motion (blurring)

13. In-Plane Resolution This is a photo that has been taken at 165x256 resolution

14. In-Plane Resolution This is a photo that has been taken with 329x512 resolution

15. In-Plane Resolution Original Resolution 720x1150

21. What is the MR image? Really just a display of the signal intensities from the voxels in the patient as pixels. No detail is seen within a voxel (pixel).

23. Voxels, FOV, and Matrix size Pixel size = FOV / matrix size Voxel size = pixel size x slice thickness FOV = field of view – can be square or rectangular (i.e., 25 cm x 25 cm, or 25 cm x 20 cm) Matrix = how many pixels in the image, square or rectangular (i.e., 256 x 256, or 256 x 192)

27. Exercise What is the voxel size? –FOV = 25 cm, Matrix = 256 x 256, ST = 1 mm –FOV = 13 cm, Matrix = 256 x 128, ST = 1 mm –FOV = 50 cm x 25 cm, Matrix = 512 x 256, ST = 5 mm

28. How detailed must the image be? The goal is to select the optimal voxel size for the anatomy and pathology you want to see

31. Sources of Noise The patient’s body Electrical devices – radio, TV, lights, motors, etc.

32. Signal-to-Noise Ratio(S/N) Two ways to increase S/N –Increase signal –Decrease noise

33. How to increase S/N Increase voxel size—this increases S –Done by increasing ST or increasing pixel size Increase field strength –increases S because S increases with increasing B 0 –Also increases N, but not as much as S, so S/N increases

34. How to increase S/N Adjust TR and TE – longer TR and shorter TE lead to increase S, and therefore, increased S/N Use better RF receive coils –Body coils are worst, small surface coils are best –New multicoil designs increase S

35. How to increase S/N Decrease receive Bandwidth (BW) BW = 1/(dwell time) Problem of increased chem shift artifact with decreased BW If you increase BW to decrease chem shift, you get more noise

36. How to increase S/N Signal averaging The number of signals averaged (NSA), or the number of excitations (NEX) or the number of acquisitions (NACQ) all mean the same thing. It is like taking multiple pictures and adding them together. The noise does not increase as much as the signal. S/N ~ sqrt (NEX), so 4 NEX doubles S/N

37. Signal-to-Noise

38. Signal-to-Noise

39. Signal-to-Noise

40. Signal-to-Noise

47. AVERAGING

48. BANDWIDTH LARGE (WIDE) SMALL (NARROW)

49. BANDWIDTH = 1/(DWELL TIME)

50. DWELL TIME SHORT sample of echo LONG sample of echo

51. PELVIS FOV 340 RFOV 65 Slice 7mm Matrix 256 Scan Percent 60 NSA 4 Time 5:54

52. KNEE FOV 160 RFOV 80 Matrix 256 Scan Percent 90 Turbo Spin Echo Slice 4 mm NSA 2 Knee Coil Time 2:28

53. WRIST Gradient Echo 3D Volume Acq. FOV 100 RFOV 80 Matrix 256 Scan Percent 80 Slice 2.4 mm Time 3:52

54. PROTOCOL FACTORS AFFECTING IMAGE DETAIL IMAGE NOISE Slice Thickness Matrix Size FOV Slice Thickness Matrix Size FOV Coil Selection Averaging Bandwidth TR and TE Field Strength