1. Swine Coccidiosis Members:Chen Hongxiu Cui Keqi Li Xiuying Luo Chuan Wang Ruijiao From:Class 1 2007

2. Introduction of swine coccidiosis Coccidians parasite at intestinal epithelial cell,and cause pig intestinal mucosa ( 粘 膜 )bleeding and diarrhea

3. Total introduction Definitive host: pig Site of infection: intestinal epithelial cell Intective stage: sporulated oocyst Diagnosis stage:oocyst

4. Morphology swine coccidiosis origins from many types ; the classifies belongs to the Sporozoa, Eucoccidia, Eimeriina,Eimeria and Isospora of Eimeriidae of spores and genera. Generally considered pathogenic strongly are Isospora suis 、 Eimeria debliecki E.scabra 、 E.spinosa.

5. Oocysts of swine coccidians Eimeria One oocyst of Eimeria contain 4 sporoblasts

6. oocysts of Isospora suis A Unsporulated Oocyst C Sporulated Oocyst One oocyst of Isospora suis contain 2 sporoblasts.

7. E.Debliecki and E.Scabra

8. Life Cycle oocyst→ sporulated oocyst→ sporozoite → trophozoite→ schizont→ merozoite→ gametocytes→ zygotes→ a new oocyst

9. Two breeding way: schizogony:schizont→gametocytes gametogony:gametocytes→zygotes Two kinds of living environment: one is feces: oocyst→sporulated oocyst the other is intestinal epithelium : sporulated oocyst→zygotes→ a new oocyst

10. Epidemiology The disease occurs in only piglet.older pigs may get more recessive infection.As the oocyst development needs the higher temperature, so the disease occur in late spring and summer sources of infections: Infective pigs and feces.

11. Routes of infections This disease is the main gastrointestinal dissemination way. When oocysts in a waste, pollution eliminated from the feed, water, soil sac or equipment etc, in suitable temperature and humidity piglets will get infectious incubation （潜伏） by the oocysts

12. Symptoms Diarrhea. Feces yellow to gray. Beginning feces loose or show paste, as the illness grew worse due to a liquid, occasionally feces three stylistically brown; And often sticks full liquid waste, and will be issued corruption milk samples calculate stink. Coat coarse disorderly, dehydration, angular, increase weight slowly. A high incidence, mortality is low

13. Isospora suis 等孢球虫感染猪的 小肠，粘膜上皮发 现的裂殖体形成裂 殖子

14. Lesions Piglets records variation is mainly chordapsus, confined by open-stope and ileum, sometimes visible necrotic enteritis, pseudomenbrane loosely adherent in hyperemia of mucous membrane.

15. 黏膜坏死病变的肠粘膜有撒糠样的伪膜

16. Diagnosis Clinically 7-21 age of piglets occurrence diarrhoea, after using common antibiotics therapy failed, a suspect about coccidiosis comes. fecal method:flotation method Scrape off jejunum and ileum mucous membrane, wipe piece dyed, find made of endogenous growth phase worm body(merozoite 、 schizont 、 gametocyte)

17. 球虫病组织学变化小肠粘膜上见不同成熟期 的球虫和小配子体、大配子体及卵囊感染

18. Treatment&Prevention Coccidiostat:Toltrazuril Prevention: 1 、 Disinfect the maternity ward ： With formaldehyde, glutaraldehyde,ethylene oxide ethane fumigation method disinfection, or basin of peracetic acid fog method, heating flame method disinfection 2 、 With amprolium feeding pigs can have good prevention effect Inactivation treatments of feces

19. 陈红秀 崔可琦 黎秀英 罗川 王睿姣