1. Some Ebola Basic Science Paul Bunge, MD, FACP October, 2014

2. Ebola EM

3. Some Thing We Know From US and Russia From Outbreaks in Congo, etc Studies in the lab, on Monkeys Vaccines and Drugs

4. Ebola Replication

5. Enveloped (easier to disinfect, but can get in mucous membranes) VP35 = interferon antagonist VP24 = interferes with interferon signaling

7. In the liverIn the skin

8. Kuhn JH, Calisher CH, ed. Filoviruses A Compendium of 40 Years of Epidemiological, Clinical, and Laboratory Studies. New York: Springer Wien, 2008: 411 pp.

10. Clinical Microbiology and Infection. July, 2011. 17(7): 964–976.

11. Results IgM early as 2 days Viral antigen 3d to 7-16 days after onset (no symptoms, no virus) Immune system suppressed Adrenal axis suppressed Bleeding <50%, with low platelets and liver dysfunction

12. www.drbunge.com