1. UPDATE ON THE SYPHILIS EPIDEMIC IN INDIANAPOLIS Janet Arno, MD and Jutieh Lincoln, MPH February 9, 2011 Marion County Public Health Department (MCPHD) Indianapolis, IN

2. Goals of this Presentation  To inform the Community about the status of the Syphilis epidemic, and to highlight its epidemiologic trends over time  To inform the Community about current efforts to control the Syphilis epidemic  To seek the help of the Community in controlling the Syphilis epidemic

3. Background  In 1999, Marion County had the highest number of Primary and Secondary (P & S) syphilis cases in the United States.  As a result of the outbreak, community organizations partnered with the Marion County Public Health Department, the State, and CDC to organize an effective campaign to control syphilis.  The number of P & S was decreased from 403 P & S cases per year to less than 50 cases per year.  In 2008 we once again saw an increase in cases twice the standard deviation of our baseline.  Now we are seeing an increase in cases superimposed on an outbreak among MSM.  Since 2008, about 410 Indianapolis residents have been diagnosed with the disease

4. Early and P & S Syphilis In Indianapolis 1996-2010

5. Early Syphilis Indianapolis 2007-2010 2007200820102009

6. Newly Diagnosed Syphilis Cases from January 1, 2010 to December 28, 2010  District 5: 178 cases  Total number of primary and secondary syphilis cases in District 5: 117  Marion County: 162 cases  Total number of primary and secondary syphilis cases in Marion County: 106  Except for race and age, the demographics of the 16 cases outside of Marion County are similar to the demographics of cases within Marion County.

7. Consistently, most cases had primary or secondary syphilis at diagnosis.

8. The outbreak has shifted from mostly Whites to mostly Blacks.

9. The outbreak has shifted from middle-aged to younger adults.

10. Males (esp. MSM) account for most cases, but female proportion has grown.

11. The HIV-infected proportion has shrunk, but many new cases do have HIV.

12. Heterosexuals account for an increasing portion of diagnosed cases.

13. Risk Behavior of Syphilis Cases  Cases frequently reported: o Sexual intercourse with unknown persons o Sexual intercourse without condom o Sexual intercourse while high on drugs such as: o Alcohol o Marijuana o Crack o Cocaine o Meth

14. Risk Behavior of Syphilis Cases  Frequently reported sites for meeting sex partners include: o Adam for Adam o Gay.com o Manhunt o Facebook o The Ten o Club Indy o Talbot o Gregs  Blacks were likely to meet their sex partners:  thru Family members  thru Friends  at social events (ex. parties)  Whites were likely to use online sites to meet their sex partners.

15. Methods of Case Detection that are being utilized in the Syphilis Epidemic  Disease Intervention Specialist (DIS)-a staff member who is trained to treat, interview, and follow up on persons diagnosed with an STD.  Patient Referral-an instance in which a person diagnosed with an STD divulges the names of partners he/she may have put at risk for that STD.  Screening-an initial evaluation conducted by a provider to determine whether a person is at risk for or has an STD.  Self Referral-an instance in which a person feels that he/she may have an STD and goes to a provider for screening.

16. Self referral and screening accounted for the bulk of the cases diagnosed.

21. Conclusions Syphilis Cases so far in 2010 surpassed 2008 and 2009’s count Blacks became majority among cases MSM still disproportionately impacted Age shifting from older to younger adults Female proportion increased to nearly 1 out of 6 syphilis cases

22. Conclusions Proportion with HIV decreasing, but still high Heterosexuals proportion trending upwards 3 risks commonly reported were: Drug use during sexual intercourse Sexual intercourse with unknown persons Sexual intercourse without condom Cases increasingly concentrated in central Marion County and lower income areas An increase is expected with waxing and waning components

23. Current Efforts  Continue to: Screen high risk groups (e.g. MSM, the incarcerated, commercial sex workers) and hard-hit areas in Indianapolis for the disease and quickly bring cases to treatment Partner with providers and community-based organizations around the city to quickly identify patients with the disease and bring them to treatment, and to educate their patients about the disease and risk reduction behaviors Aggressively follow up with partners named by cases to determine if they have the disease and bring them to treatment or to educate them about risk reduction behaviors

24. Current Efforts  Continue to Periodically update providers, public health practitioners, and the community on the epidemic through mass mailing and through MCPHD website. A powerpoint presentation on the epidemic is available at: http://www.mchd.com/syphilis_info.htmhttp://www.mchd.com/syphilis_info.htm  Have set up a new website (http://www.bellflowerclinic.org/) to keep providers, public health practitioners, and the community informed about clinic hours, STD resources, services offered, and to answer their questionshttp://www.bellflowerclinic.org/

25. How Can You Help?  Spread the word about the Syphilis epidemic  Encourage persons in your community to get tested for Syphilis  Inform persons in your community that Bell Flower Clinic offers low cost STD screening (or free STD screening with life saver card)  Share ideas for screening sites in your community  Serve as an information resource for your community  Offer Suggestions on how to control the epidemic

26. Acknowledgement A Special thank you to Mr. David Broyles (Marion County Public Health Department Corporate Information Systems) for his excellent and timely work on the Syphilis maps, and Caitlin Gill (Epidemiology intern from the IU Department of Public Health) for assisting in the compilation and presentation of this data.