1. Chapter 11 Skeletal System

2. Points to Ponder What are the 5 functions of the skeletal system? What are the parts of a long bone? How do bones grow, remodel and repair? How are hormones involved in bone growth? What is osteoporosis? How are age, gender and ethnicity determined through skeletal remains? What are the components of the axial and appendicular skeletons? What are synovial joints and what kind of angular movements to they allow?

3. What are the functions of the skeletal system? 1.Supports the body 2.Protects the soft body parts 3.Produces blood cells 4.Stores minerals (calcium and phosphate) and fat 5.Allows for movement by attaching muscles 11.1 Overview of the skeletal system

4. What is the anatomy of a long bone? Diaphysis – shaft of the bone made of compact bone and filled with yellow marrow Epiphysis – ends of the bone made mostly of spongy bone Articular cartilage – hyaline cartilage found on the ends of long bones Yellow bone marrow – stores fat Red bone marrow – makes blood cells found in spongy bone and flat bones Periosteum – living, outer covering of fibrous connective tissue Ligaments – fibrous connective tissue that connects bones 11.1 Overview of the skeletal system

5. More detail on bone… Compact bone –Composed of osteons with a central canal containing blood vessels –Contains living bone cells called osteocytes chambers called lacunae Spongy bone –Made of plates with spaces filled with red bone marrow 11.1 Overview of the skeletal system

6. Where are the 3 types of cartilage found? Cartilage – flexible connective tissue categorized based on the type and arrangement of matrix fibers Types: –Hyaline cartilage – ends of long bones, nose, ends of ribs, larynx and trachea –Fibrocartilage – disks between vertebrae and in the knee; stronger than hyaline cartilage –Elastic cartilage – ear flaps and epiglottis; more flexible than hyaline cartilage 11.1 Overview of the skeletal system

7. What are the important cells in bone growth, remodeling and repair? Osteoblasts – bone-forming cells Osteocytes – mature bone cells that maintain bone structure derived from osteoblasts Osteoclasts – bone-absorbing cells Chondroytes – cartilage-forming cells 11.2 Bone growth, remodeling and repair

8. How does bone develop? Ossification - the formation of bone in two distinct ways: 1.Intramembranous ossification - bone development between sheets of fibrous connective tissue; used in flat bones 2.Endochondrial ossification – cartilage is replaced by bone; used by most bones 11.2 Bone growth, remodeling and repair

9. How does endochondral ossification occur? 1 st Cartilage model – chondrocytes lay down hyaline cartilage in the shape of the future bones 2 nd Bone collar formation – osteoblasts secrete bone matrix and results in a collar made of compact bone 3 rd Primary ossification center – osteoblasts are brought interiorly by blood and lay down spongy bone 4 th Secondary ossification sites – bone centers in the epiphyses formed after birth 5 th Epiphyseal plate – a cartilage band that acts as a growth plate that allows bones to lengthen 11.2 Bone growth, remodeling and repair

10. Visualizing endochondral ossification 11.2 Bone growth, remodeling and repair

11. How do bones lengthen? 11.2 Bone growth, remodeling and repair

12. How do hormones affect bone growth? Growth hormone (GH) – stimulates general bone growth and the epiphyseal plates Sex hormones – increases growth during adolescence Vitamin D – converted to a hormone to allow calcium absorption in the intestine 11.2 Bone growth, remodeling and repair

13. What is bone remodeling and what is its role in homeostasis? Bone remodeling – bone renewal at a rate of up to 18% per year Remodeling allows bones to respond to stress Regulates the calcium in the blood through hormones: –Parathyroid hormone (PTH) – increases blood calcium by accelerating bone recycling –Calcitonin – decreases blood calcium 11.2 Bone growth, remodeling and repair

14. Health focus: Osteoporosis Osteoporosis – bones are weakened due to a decreased bone mass Bone reabsorption exceeds absorption usually by age 40 Risk factors: women, white or Asian, thin, family history, early menopause, smoking, diet low in calcium, excessive caffeine or alcohol consumption and a sedentary lifestyle Can lead to fractures and other complications Can be treated with drugs, hormones and lifestyle change 11.2 Bone growth, remodeling and repair

15. Steps in bone repair Hematoma (6-8 hrs.) – blood clot formed between broken bones Fibrocartilaginous callus (~ 3 weeks) – cartilaginous callus forms between broken bones Bony callus (3-4 months) – cartilaginous callus is turned to bone Remodeling – old bone tissue is replaced by new bone tissue 11.2 Bone growth, remodeling and repair

16. Bone repair 11.2 Bone growth, remodeling and repair

17. The 206 bones of the skeleton 11.3 Bones of the axial skeleton

18. Science focus: Skeletal remains Characteristics to be determined: 1.Age: approximated through dentition, studying areas of bone ossification and joint condition 2.Gender: pelvic bone is best used, thickness of long bones, skull characteristics 3.Ethnicity: difficult to tell but skull characteristics are most useful 11.3 Bones of the axial skeleton

19. The axial skeleton Skull – made of cranium and facial bones Hyoid bone Vertebral column – vertebrae and intervertebral disks Rib cage – ribs and sternum 11.3 Bones of the axial skeleton

20. The skull – the cranium Cranium –Protects the brain –Composed of 8 bones –Some contain sinuses 11.3 Bones of the axial skeleton

21. Bones of the face and the hyoid bone Facial bones –Mandible –Maxillae –Zygomatic bones –Nasal bones Hyoid –Only bone that does not articulate with another bone 11.3 Bones of the axial skeleton

22. The vertebral column Types of vertebrae –33 vertebrae Cervical (7) Thoracic (12) Lumbar (5) Sacrum (5 fused) Coccyx (4 fused into tailbone) Intervertebral disks –Fibrocartilage between vertebrae 11.3 Bones of the axial skeleton

23. The rib cage Ribs – protects heart and lungs –Flattened bone originating from the thoracic vertebrae –12 pairs: 7 pr. true ribs 3 pr. false ribs 2 pr. floating ribs Sternum –Known as the breastbone 11.3 Bones of the axial skeleton

24. The appendicular skeleton Pectoral girdle and upper limb Pelvic girdle and lower limb 11.4 Bones of the appendicular skeleton

25. The appendicular skeleton Pectoral girdle –Scapula and clavicle Upper limb –Arm and hand bones 11.4 Bones of the appendicular skeleton

26. The appendicular skeleton Pelvic girdle –coxal bone Lower limb –Leg and foot bones 11.4 Bones of the appendicular skeleton

27. Types of joints (where bones meet bones) Fibrous – usually immovable such as the sutures between cranial bones Cartilaginous – tend to be slightly movable such as the intervertebral disks Synovial – freely movable joints such as the ball-and-socket hip and shoulder joints and the knee joint 11.5 Articulations

28. Anatomy of a synovial joint 11.5 Articulations

29. Summary of synovial joints movements Flexion – decrease in joint angle Extension - increase in joint angle Adduction – body part moves toward midline Abduction – body part moves away from midline Inversion – sole of foot turns inward Eversion – sole of foot turns outward 11.5 Articulations

30. Visualizing synovial joints movements 11.5 Articulations