2. ATS 3f® Aortic Bioprosthesis
The first evolution in the design series
Based on early study of embryology and valve function
From a simple TUBE to a tubular 3-leaflet structure
Form Follows Function (3f)

3. ATS 3f® Aortic Bioprosthesis
New design in holder implant system
Designed for easy and reproducible implantation
Single suture line with attachment of commissural tabs

4. ATS 3f® Aortic Bioprosthesis
Studies show valves unique design maintains shape and function of aortic valve sinus1
ATS 3f® Bioprosthesis
Normal Aortic Valve
1. Data on file. ATS Medical, Inc.

5. ATS 3f Enable™ Aortic Bioprosthesis
The second evolution in the design series
Use of only guiding sutures at implantation
< 2 minute insertion time
Self-expanding
Nitinol™ frame
Same revolutionary
tubular design
leaflet structure
ATS 3f Enable
Bioprosthesis

6. ATS 3f Enable™ Aortic Bioprosthesis
Prosthesis insertion < 2 minutes
1. Valve folded in delivery system
2. Plunger places valve in the annulus
3. Valve expands in place

7. The ATS 3f Entrata™ Aortic Valve System
The third evolution in the design series
Designed for minimally invasive, trans-apical, and percutaneous delivery
• Stainless steel frame
• Same tubular bioprosthesis

8. ATS 3f Entrata™ Aortic Valve System
Trans-apical delivery
Beating heart
1. Balloon inserted to open diseased valve
2. Valve inserted into the annulus and expanded

9. ATS 3f Entrata™ Aortic Valve System
New technologies in:
Valve balloon
delivery system
Crimped valve
through trocar
Fluroscopy showing
valve dilatation and
competence

10. Evolutionary Approach to Aortic Valve Replacement
ATS 3f® Aortic
Bioprosthesis
Revolutionary tubular
design

11. Evolutionary Approach to Aortic Valve Replacement
ATS 3f Enable™
Aortic Bioprosthesis
Sutureless self-
expanding stent
ATS 3f® Aortic
Bioprosthesis
Revolutionary tubular
design

12. Evolutionary Approach to Aortic Valve Replacement
ATS 3f Entrata™
Aortic Valve
System
Beating heart,
minimally invasive
delivery
ATS 3f Enable™
Aortic Bioprosthesis
Self-expanding stent
ATS 3f® Aortic
Bioprosthesis
Revolutionary tubular
design

13. The Future is Present with ATS Medical