1. Hunger and satiety in anorexia nervosa: fMRI during cognitive processing of food pictures Santel et al., 2006 Maria Zuluaga Bsc Psychology 14’

2. Brief overview 0 Anorexia nervosa- what is it? 0 Mental disorder 0 Fear of gaining weight 0 Mostly seen in adolescents (14 years old) 0 More frequent in women- 0 amenorrhea (endocrine disorder) 0 Lower activation in certain brain areas helps to maintain fasting

3. Introduction 0 Objective: to test the different effects of visual stimuli of food on healthy and anorexic people. 0 BUT- making a distinction between: 0 A Hungry state 0 A Satiated state

4. Hypothesis 0 In anorexic patients- weaker activation in: 0 Inferior parietal lobe (IPL) 0 Occipital cortex 0 Higher activation in: 0 Medial prefrontal cortex

5. Experimental Task 0 20 practice trials 0 8 am- 2 sessions (30 min) 0 8 consecutive blocks 10 stimuli (colored pictures) 0 food (320) 0 non food (320) Is the picture A) Pleasant B) Neutral C) unpleasant

6. Results 0 Are you hungry? 0 Higher response when hungry (both). 0 Anorexics had a lower report overall. 0 Anorexic- less pleased by food stimuli. 0 Fmri- 0 Anorexics (satiated)- lower activation on IPL 0 (-) correlation with stornger dietary restrain. 0 (+) correlation with weaker disinihbition of eating and low BMI. 0 Anorexic (hungry)- decreased activation of occipital cortex.

7. Discussion 0 Lower activation on IPL 0 This area controls: 0 Appetite 0 Food related behaviors 0 Satiation 0 Contains primary somatosensory neurons for body parts involved in eating. 0 Facilitates fasting

8. 0 Lower occipital cortex activation 0 Attentional motivation 0 Focus on food stimuli when hungry to maintain fasting 0 1° and 2° visual areas- importance of stimuli 0 Lower activation when anorexic patient was hungry.

9. Strengths & Limitations 0 Clear explanations 0 Procedure 0 Results 0 Great build up on background information 0 Sample size 0 Non compliance 0 Organization 0 Hard to follow

10. Opinion 0 Easy to understand overall 0 Explains why some behaviors may arise. (makes sense) 0 Comparison to obese people

11. Enjoy what you have, it’s beautiful!