1. Martin Neovius, PhDFinn Rasmussen, MD/PhD Dept of MedicineDept of Public Health Karolinska Institute Stockholm, Sweden Trends in and Consequences of Overweight in Swedish Men

2. Contents Prevalence  BMI distribution in Swedish men 1969-2005  Trends in obesity and morbid obesity 1969-2005  Geographical trends in overweight 1969-2005  Geographical trends in obesity 1969-2005 Consequences of Overweight and Obesity  Premature death  Preterm retirement  Cardiovascular Disease

4. 23/05/2015 Obesity and Morbid Obesity (1969-2005) Neovius M, Teixeira-Pinto A, Rasmussen F. Shift in the composition of obesity in young adult men in Sweden over a third of a century. Int J Obes (Lond). May 2008;32(5):832-836.

5. BMI Distribution (1969-2005) Neovius & Rasmussen (unpublished data)

6. BMI ≥ 25 Height and weight measured at mandatory military conscription tests Age 18.3y (SD 0.4y; range 17-20y) n=1.6 million Overweight

7. 23/05/2015

14. BMI ≥ 30 Height and weight measured at mandatory military conscription tests Age 18.3y (SD 0.4y; range 17-20y) n=1.6 million Obesity

15. 23/05/2015

22. HEALTH CONSEQUENCES Premature Death Disability Pension Cardiovascular Disease

24. Neovius, Sundström & Rasmussen, BMJ 2009;338:b496 Incidence rates of premature death illustrating the combined effects of overweight and smoking status (n=45 920; 2897 deaths; 1.7m person-years)

25. Neovius, Sundström & Rasmussen, BMJ 2009;338:b496 Relative risk of premature death illustrating the combined effects of overweight and smoking status (n=45 920; 2897 deaths; 1.7m person-years)

26. Cumulative Mortality by BMI Status Neovius, Sundström & Rasmussen, BMJ 2009;338:b496

27. Cumulative Mortality by Smoking Status Neovius, Sundström & Rasmussen, BMJ 2009;338:b496

28. Risk of Premature Death: Interaction between BMI and Smoking

30. Associations between BMI Status in Late Adolescence and Future Disability Pension BMI ≥ 35 BMI 30-34.9 BMI 18.5-24.9 BMI 25-29.9 BMI <18.5 Neovius M, Kark M, Rasmussen F. Association between obesity status in young adulthood and disability pension. Int J Obes (Lond). Aug 2008;32(8):1319-1326. Unadjusted estimates Not adjusted for muscle strength, socio- economic status, geographical region or year

31. Relative Risk Increase for Disability Pension (vs. normal weight men) Adjusted for muscle strength, socio-economic status, geographical region and year Neovius M, Kark M, Rasmussen F. Association between obesity status in young adulthood and disability pension. Int J Obes (Lond). Aug 2008;32(8):1319-1326. Normal weight OverweightUnderweight

33. Risk of Disability Pension by BMI and Smoking Status Neovius K, Neovius M, Rasmussen F. The combined effects of overweight and smoking in late adolescence on subsequent disability pension: a nationwide cohort study. Int J Obes (Lond) 2009.

34. Risk of Disability Pension: Interaction between BMI and Smoking Neovius K, Neovius M, Rasmussen F. The combined effects of overweight and smoking in late adolescence on subsequent disability pension: a nationwide cohort study. Int J Obes (Lond) 2009.

36. Risk of Cardiovascular Disease: Interaction between BMI and Blood Pressure

37. Neovius M, Sundström J, Rasmussen F. Combined Effects of Overweight and Smoking in Late Adolescence on Subsequent Mortality: Nationwide Cohort Study BMJ 2009;338:b496 Neovius M, Teixeira-Pinto A, Rasmussen F. Shift in the composition of obesity in young adult men in Sweden over a third of a century. Int J Obes (Lond). May 2008;32(5):832-836. Neovius M, Rasmussen F. Place of residence and obesity in 1,578,694 young Swedish men between 1969 and 2005. Obesity (Silver Spring). Mar 2008;16(3):671-676. Neovius M, Kark M, Rasmussen F. Association between obesity status in young adulthood and disability pension. Int J Obes (Lond). Aug 2008;32(8):1319-1326. Silventoinen K, Magnusson PK, Neovius M, Sundstrom J, et al. Does obesity modify the effect of blood pressure on the risk of cardiovascular disease? A population-based cohort study of more than one million Swedish men. Circulation 2008;118(16):1637-42. Neovius K, Neovius M, Rasmussen F. The combined effects of overweight and smoking in late adolescence on subsequent disability pension: a nationwide cohort study. Int J Obes (Lond) 2009. Details on study population