2. for the Psychiatry Clerkship

3. is proud to present And Now Here Is The Host... Insert Name Here

4. The categories for today’s Jeopardy on Substance Use will be:

5. Marijuana

6. Nicotine

7. Alcohol

8. LSD, XTC, PCP Inhalants

9. Miscellaneous

10. 100 200 300 800 700 500 800 Marijuana Alcohol Miscellaneous 100 700 500 700 400 800 600 100 900 300 500 800 LSC, PCP, XTC, Inhalants 100 900 500 400 300 200 300 400 600 800 200 300 600 200 500 400 700 600 200 400 700 600 Nicotine

11. Row 1, Col 1 Use of a single joint can lead to a positive urine marijuana test as many as this number of days later What is 4 days?

12. 1,2 Use of marijuana at an early age may interact with those who have the genetic predisposition & promote the development of this serious mental illness What is schizophrenia?

13. 1,3 The most common psychiatric adverse side effects of marijuana use is psychosis and this What is anxiety/panic attacks?

14. 1,4 Cognitive effects of marijuana include amotivation, disorientation, unsteady coordination, altered perception, decreased consciousness and this reason for poor academic performance What is memory loss?

15. 1,5 10, 20, 30, 40, 50 The percent of users who become dependent on marijuana is this What is 10%?

16. 1,6 This synthetic Cannabinoid agonist is used to treat anorexia and weight loss in AIDS pts & nausea/vomiting in pts getting chemo What is dronabinol (marinol)

17. 1,7 Marijuana’s clinical properties include: anti-inflammatory effects anti-convulsant effects and anti- this effect What is anti-emetic?

18. 1,8 Potentially life threatening; Significant discomfort; Mild symptoms; This most commonly describes withdrawal from marijuana What is mild symptoms?

19. 1,9 Marijuana use that leads to a reduction in prosocial goal directed activities that may contribute to poor school or job performance is commonly called this What are amotivational syndrome?

20. 2,1 This non-nicotine agent is thought to increase dopamine and norepinephrine levels and mimic some of the effects of nicotine What is Bupropion (Wellbutrin)?

21. 2,2 This smoking cessation medication is a long acting partial agonist at the α 4 β 2 NAR What is varenicline (chantix)?

22. 2,3 This tricyclic antidepressant is not first line but a second line smoking cessation agent due to its side effect profile What is nortriptyline?

23. 2,4 It is unusual to rare for an individual to start smoking after this age What is 21?

24. 2,5 Nicotine withdrawal from smoking cessation usually begins within 24 hours, and peaks at this time after cessation What is day 2-3?

25. 2,6 Nicotine withdrawal from smoking cessation usually will last this long What is 2-3 weeks?

26. 2,7 This alpha-2 adrenergic agonist is used for treating hypertension but has shown promise for smoking cessation What is clonidine?

27. 2,8 The most common tobacco use product is this What is cigarettes?

28. 2,9 Disappearance of nausea and dizziness despite repeated tobacco use is an indication of this What is tolerance?

29. 3,1 For ♀ & older adults, a social or moderate drinker is one who does not binge drink & consumes no more than this number of drinks per day on average What is one?

30. 3,2 These type of peptides mediate some of alcohol’s rewarding effects by enhancing the midbrain release of dopamine What is opioid?

31. 3,3 This medication inhibits aldehyde dehydrogenase leading to a build up of acetaldehyde and negative reinforcement of alcohol use What is disulfiram (antabuse)?

32. 3,4 This medication that is used in the treatment of alcohol dependence is available in a monthly depot injection What is naltrexone (vivitrol)?

33. 3,5 These two medications are contraindicated in pts with significantly compromised liver function What are disulfiram (anatbuse) and naltrexone (vivitrol)?

34. 3,6 For ♂ who are < 65 y/o, a social or moderate drinker is one who does not binge drink &consumes no more than this number of drinks per day on average What is two?

35. 3,7 This medication is an opioid mu receptor antagonist as a treatment option What is naltrexone (vivitrol)?

36. 3,8 This medication helps prevent relapse, has a common side effect of diarrhea, is safe in hepatic compromised pts, but is contraindicated in pts with severe renal disease What is acamprosate (campral)

37. 3,9 Naltrexone is most effective in treating this aspect of alcohol dependence What are cravings?

38. 4,1 Standard drug screens do not detect these drugs and usage typically declines dramatically after the teen years What is inhalants?

39. 4,2 The phenylalkylamines class of hallucinogens includes mescaline, DOM, and this most well known drug What is MDMA (ecstasy, XTC)?

40. 4,3 First developed as a anesthetic, this drug produces feelings of separation from mind and body-dissociation What is Phencylcidine (PCP)?

41. 4,4 MDMA, LSD, or PCP: Continued use of this hallucinogen has been linked to neurotoxic effects What is MDMA (ecstacy)?

42. 4,5 Any inhaled volatile hydrocarbons (glues, fuels, paints) may produce “sudden sniffing death” due to this What is cardiac arrhythmia?

43. 4,6 Phencylclidine (PCP) can be detected in the urine up to this many days after use What is 8?

44. 4,7 The ergoline class of hallucinogens includes this drug which often produces visual hallucinations which can be frightening to the use What is lysergic acid diethylamide (LSD)?

45. 4,8 While lab testing can detect PCP, may or may not be helpful detecting hallucinogens, lab testing is not helpful detecting this What are inhalants?

46. 4,9 Intoxication with this drug may produce vertical or horizontal nystagmus, diminished responsiveness to pain, and violent behavior What is Phencyclidine (PCP)?

47. 5,1 The proportion of users of this are most likely to become dependent on the substance What is nicotine?

48. 5,2 Use of this illicit drug is most commonly involved in ER visits What is cocaine?

49. 5,3 When sober, users of this drug(s) may re-experience geometric visual hallucinations, flashes of color, intensified colors, or misperception of objects being too large or too small What are hallucinogens? (Primarily LSD)

50. 5,4 About 50% of people who attempt to quit smoking develop withdrawal and commonly complain of irritability, difficulty concentrating, and this What is anxiety?

51. 5,5 Over 80% of tobacco users attempt to quit, 60% relapse within 1 week, and this number succeed and do not ever relapse What are 1 in 20 (5%)?

52. 5,6 A drink is defined as a 1.5 ounce shot, this 4-6 ounces of wine, or this many ounces of beer What are 12?

53. 5,7 Psychostimulants specifically worsen this symptom of schizophrenia What are hallucinations? And paranoia

54. 5,8 Use of marijuana, alcohol, or this before age 15 are considered to be the three “Gateway Drugs” to later dependence problems What is nicotine?

55. 5,9 The most common illicit drug used worldwide across all age groups is this What is marijuana?