1. Muscle Physiology

2. Contraction Speed Figure 12.23
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3. Oxidative and Glycolytic Fibers
Figure 12.24
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4. Muscle Fatigue
Figure 12.25
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5. Muscle Attachments Figure 12.26
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6. Antagonistic Muscles Figure 12.27
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7. Muscle Spindle
Figure 12.28
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8. Muscle Spindle Responses
Figure 12.29
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9. Alpha / Gamma Coactiviation
Figure 12.30
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10. Golgi Tendon Organs Figure 12.31
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11. Muscle Tissue Types Figure 12.32
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12. Properties of Smooth Muscle
One nucleus
Tropomyosin
No troponin
Dense bodies analogous to Z line
Slow myosin ATPase
Myosin has light chains
Little sarcoplasmic reticulum
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13. Smooth Muscle Cell Figure 12.33
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14. Excitation-Contraction Coupling
Ca2+
Calmodulin
Phosphorylated
myosin light
chain
Unphosphorylated
Endoplasmic
reticulum
No myosin
ATPase activity
No crossbridge
activity
Myosin ATPase
active
Crossbridge
cycling
Contraction
Smooth muscle cell
MLCK
Ca-calmodulin
Figure 12.34
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15. Single-Unit Muscle Figure 12.35b
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16. Properties of Single-Unit Smooth Muscle
Gap junctions
Pacemaker cells with spontaneous depolarizations
Innervation to few cells
Tone = level of contraction without stimulation
Increases/decreases in tension
Graded Contractions
No recruitment
Vary intracellular calcium
Stretch Reflex
Relaxation in response to sudden or prolonged stretch
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17. Multi-Unit Muscle Figure 12.35a
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18. Multi vs. Single-Unit Muscle
Figure 12.35
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19. Spontaneous Depolarizations
Figure 12.36
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20. Cardiac Muscle
Figure 12.37
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21. Muscle Comparisons Table 12.2
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