1. بسم الله الرحمن الرحیم

2. Muscular system

3. Type of Muscles Skeletal Muscle Cardiac Muscle Smooth Muscle

4. Diameter of Skeletal Muscle Specific Muscle Age Sex State of Nutrition Physical Training HHypertrophy HHyperplasia

5. Organization of Skeletal Muscle

6. Skeletal Muscle

7. Organization of Skeletal Muscle

8. Organizati on of Skeletal Muscle Fiber

9. Cross Striation

10. Myofilaments Thin filament  Actin  Tropmyosin  Troponin Thick filament  Myosin

11. G Actin Thin Filament F Actin Troponin Tropomyosi n

12. Thin filament

13. Thick Filament Myosin

14. Actin & myosin Summary Slide

15. Myosin

16. Actin & myosin Summary Slide

17. Organization of the Myofilaments

18. Myofilaments

19. T Tubule Terminal Cisternae Sarcoplasmic Reticulum Triad Sarcolamma & Sarcoplasmic Reticulum

20. triad

22. Transmission of the signal to SER

23. Contraction Mechanism

24. Contraction mechanism

28. Myofilaments

29. Myotendineal Junction

30. Innervation

31. Myasthenia Gravis Autoimmune Disorder Prograssive mascular weakness Reduction of acetylcholin receptors

32. Type of skeletal muscle Type I: slow, red oxidative fibers  many mitochondria and myoglobin  Gain energy by aerobic oxidative phosphorilation  Prolong contraction  Back muscle

33. Type of skeletal muscle Type IIa:fast, intermediate oxidative-glycolytic fiber  many mitochondria and myoglobin  Considerable glycogen  Both oxidative and anaerobic glycolysis  Rapid contraction short burst of activity

34. Type of skeletal muscle Type IIb: fast, white glycolytic fibers  fewer mitochondria, less myoglobin and abundant glycogen  Depend on glycolysis  Adapt for rapid contraction

35. Skeletal muscle types

36. Myogenesis (Straited Muscle)

37. Muscle Spindle Intrafusal muscle fibers  Nuclear chain fibers  Nuclear bag fibers Extrafusal muscle fibers

40. Cardiac Muscle

43. Cardiac Muscle intercalated Disc

44. Cardiac Muscle

45. Diad & Intercalated disc In Cardiac Muscle cell

46. Smooth muscle

47. Smooth Muscle

48. Smooth muscle contraction

49. Smooth Muscle cell

51. Smooth Muscle

53. Contraction mechanism