1. Case study university: best practice health research collaboration Dr David Langley & Prof Peter Mathieson

2. Introductions and background Dr David Langley Director of Research and Enterprise Development Prof. Peter Mathieson Dean of Medicine and Dentistry

3. Summary The Bristol context Bristol’s challenges Bristol’s vision How Bristol is responding Lessons learned Discussion

4. The Bristol context 2 Universities University of Bristol University of the West of England 4 NHS Trusts NHS Bristol (& 2 other local PCTs) University Hospitals Bristol NHS FT North Bristol NHS Trust Avon and Wiltshire Mental Health Partnership Strong regional, national and international collaborations

5. Bristol’s challenges Meet local and regional health needs Build on strong foundation of existing activity and collaboration Partner, integrate and respond strategically Facilitate new ideas and new relationships Accelerated adoption of research innovations Increase and enhance links with industry See our dispersed geography as an asset

6. But…. University of Bristol Medical School had dreadful RAE2001 outcome much improved in RAE2008 Relationship between 2 local HEIs was not ‘tight’ Relationship between NHS partners was fragmented and little association with HEIs Little coordination or interaction with research Yet some great research going on despite this!

7. How Bristol is responding Severnside Alliance for Translational Research (SARTRE) Bristol research and Innovation Group for Health (BRIG-H) HIEC South West AHSC Continue to do great research and innovation

8. SARTRE Partnership Universities of Cardiff and Bristol, funded by MRC Joint Professor of Practice in Translational Medicine (Lars Sundstrom) Merge efforts in translational health research A focal point for interactions with the Bio- Pharmaceutical industry Successful MRC-DPFS devolved portfolio scheme

9. BRIG-H Bristol-wide partnership (4 NHS Trusts, 2 HEIs) Decisive, active leadership by Vice- Chancellors and Trust CEOs Led by Dean of Medicine, supported by senior colleagues from all 6 organisations Integrated strategic approach to research and innovation Focused ambitious programme Address barriers to effective collaboration

10. Structure

11. BRIG-H Joint events and symposia such as Bris’10 Joint appointments – NHS R&D Director Regular dialogue at many levels of organisations Activities such as cancer strategy sponsored through BRIG-H AHSC planning…..

12. http://www.bristol.ac.uk/fmd/brigh.html Strategic partnership between: University of Bristol University of the West of England NHS Bristol University Hospitals Bristol NHS Foundation Trust North Bristol NHS Trust Avon & Wiltshire Mental Health Partnership NHS Trust

13. BRIG-H Strategic Aims To improve the health of people in Bristol, the UK and beyond through better co-ordination of research, innovation and resources To realise the full potential of health-related research and innovation in Bristol through effective partnership working To foster excellence in people and infrastructure that impact on health-related research and innovation To develop Bristol’s reputation for excellence and promote it nationally and internationally

14. Population Health Major Programme Funding and Project Grants Strategic Research Themes Strategic Cross-cutting Platforms Bristol Health Research Strengths Bristol Health Research Strengths Imaging Translational Research Methodology Research Frontier Science & Technology Major Funded Units & Centres Children & Young People Mental Health & Addiction Musculoskeletal Oral Health & Disease Cancer Neuroscience Infection & Immunity Cardiovascular

15. HIEC- SW A single HIEC for the South West Multi-partner organisation Promote pan-regional uptake and rapid diffusion of innovation into healthcare Measure the improvement in quality Develop a multi-professional workforce that is actively engaged in innovation.

16. AHSC Bristol was unsuccessful in ‘official’ DoH AHSC call Nevertheless, broad agreement that we need to start to behave like one Project has started to realize this aim with all BRIG-H partners

17. Ongoing challenges Politics – uncertainties, possibility of merging NHS Trusts Shared ambition – for Bristol and beyond? Different drivers and processes – national level Delivery – both ‘bottom up’ and ‘top down’ Stakeholder buy-in - need to see changes soon, not everyone agrees with vision Governance – not easy but Leadership driven Sustainability - funding and investment

18. Lessons learned (& in progress!) Essential first step is convincing partner organisations (at senior level) that each is not strong enough on its own and that together we can be greater than the sum of the parts Money is a powerful motivator! Individuals can make or break initiatives Frequent frank dialogue is essential “Big picture” is best antidote to parochialism

19. The opportunity: NIHR funding for clinical research in England

20. This is a time of unprecedented opportunity for biomedical research......how well-placed are you in Canterbury to seize the opportunities?

21. Promoting excellence in health research: Opportunities and challenges Woburn House Conference Centre, London, WC1H 9HQ Thursday 11 March 2010 Session 2 12.00Discussion groups Delegates should choose to attend one group from the list below. Places are allocated on a first-come, first-served basis and are subject to maximum capacities. Promoting good conduct in research James Parry, Acting Head, UK Research Integrity Office Making UK teaching hospitals more attractive for research (led by the Medical Schools Council and Association of UK University Hospitals) Professor Chris Day, Pro Vice Chancellor, Medical Sciences, Newcastle University, and Mr Malcolm Lowe-Lauri, Chief Executive, University Hospitals of Leicester NHS Trust Case study university: best practice health research collaboration Dr David Langley, Director, Research and Enterprise Development University of Bristol, and Professor Peter Mathieson, Dean of Medicine, University of Bristol Impact and user value Drs Astrid Wissenburg, Chair, Research Councils UK (RCUK) Knowledge Transfer and Economic Impact Group and Director of Communication and Information ESRC Session 1 10.00 Welcome and introduction by Conference Chair Professor Michael Farthing, Chair, Health and Social Care Policy Committee, Universities UK; Vice-Chancellor, University of Sussex 10.10The evolving model of pharmaceutical R&D Dr Malcolm Skingle CBE, Association of the British Pharmaceutical Industry (ABPI) 10.30Making the UK a centre for research excellence Professor Dame Sally C. Davies, Director General of Research and Development, Department of Health 10.50The contribution of higher education to the health research agenda Professor Don Nutbeam, Vice-Chancellor, University of Southampton Case study university: best practice health research collaboration Dr David Langley, Director, Research and Enterprise Development, and Professor Peter Mathieson, Dean of Medicine, University of Bristol

22. Discussion