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Gene Mutations Worksheet

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Presentation on theme: "Gene Mutations Worksheet"— Presentation transcript:

1 Gene Mutations Worksheet

2 Insertion Mutation TAC GGA CGA TCT CAG GAG CCT ATA ATC
TAC AGG ACG ATC TCA GGA GCC TAT AAT AUG UCC UGC UAG AGU CCU CGG AUA UUA methionine-serine-cysteine-stop

3 Deletion Mutation TAC GGA CGA TCT CAG GAG CCT ATA ATC
TAC GAC GAT CTC AGG AGC CTA TAA AUG CUG CUA GAG UCC UCG GAU AUU methionine-leucine-leucine-glutamic acid-serine-serine-aspartic acid-isoluecine

4 TAC CAT GCA GAT CTG GCC CAG TTC ATC
Base Substitution Mutation (Transversion Mutation = purine swapped with pyrimidine or vice versa) TAC CAT GCA GAT CTG GCC CAG TTC ATC TAC CCT GCA GAT CTG GCC CAG TTC ATC AUG GGA CGU CUA GAC CGG GUC AAG UAG methionine-glycine-arginine-leucine-aspartic acid-arginine-valine-lysine-stop

5 TAC GTC GCT CAA CGG GAC CTG ACC ACT
Base Substitution Mutation (Transition Mutation = purine swapped with purine or pyrimidine with pyrimidine) TAC GTC GCT CAA CGG GAC CTG ACC ACT TAC ATC GCT CAA CGG GAC CTG ACC ACT AUG UAG CGA GUU GCC CUG GAC UGG UGA methionine-stop

6 Base Substitution Mutation (Silent Mutation)
TAC CAT TCT CGG TGT AAA AGG GCG ATT TAC CAC TCT CGG TGT AAA AGG GCG ATT AUG GUG AGA GCC ACA UUU UCC CGC UAA methionine-valine-arginine-alanine-threonine-phenylalanine-serine-arginine-stop No change in aa sequence!

7 Base Substitution Mutation (Nonsense Mutation)
TAC GGT AAT CAA ATA GAA CCT GAG ACT TAC GGT AAT CAA ATA GAA ACT GAG ACT AUG CCA UUA GUU UAU CUU UGA CUC UGA methionine-proline-leucine-valine-tyrosine-leucine-stop

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