2. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which of these study designs can provide the best evidence? B. RCT with meta- analysis D. Uncontrolled case series C. Computer database analysis A. Meta-analysis with individual data

3. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html A. Meta-analysis with individual data B. RCT with meta- analysis C. Computer database analysis D. Uncontrolled case series Which of these study designs can provide the best evidence?

4. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html B. RCT with meta- analysis Which of these study designs can provide the best evidence? A. Meta-analysis with individual data

5. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which of these study designs can provide the best evidence? A. Meta-analysis with individual data

6. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html What is the estimate of the mean time to conduct a systematic review and meta- analysis? B. 630 hours D. 1530 hoursC. 1140 hours A. 2210 hours

7. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. 1530 hours A. 2210 hoursB. 630 hours C. 1140 hours What is the estimate of the mean time to conduct a systematic review and meta- analysis?

8. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html C. 1140 hours What is the estimate of the mean time to conduct a systematic review and meta- analysis?

9. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html What is a ‘kin’ study? D. A study using the same trial design B. A study of parents and their children C. A study using the same patient population A. A study where the authors are related

10. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. A study using the same trial design B. A study of parents and their children A. A study where the authors are related C. A study using the same patient population What is a ‘kin’ study?

11. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. A study using the same trial design C. A study using the same patient population What is a ‘kin’ study?

12. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html C. A study using the same patient population What is a ‘kin’ study?

13. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which statement identifies good meta-analysis and systematic review processes? B. PRISM D. STROBEC. COCHRANE A. CONSORT

14. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. STROBEC. COCHRANE B. PRISM A. CONSORT Which statement identifies good meta-analysis and systematic review processes?

15. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html B. PRISM C. COCHRANE Which statement identifies good meta-analysis and systematic review processes?

16. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which statement identifies good meta-analysis and systematic review processes? B. PRISM

17. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which is not a discrete effect size measure used in meta-analysis? D. RD B. RR C. NNT A. OR

18. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. RD B. RRA. OR C. NNT Which is not a discrete effect size measure used in meta-analysis?

19. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html C. NNT Which is not a discrete effect size measure used in meta-analysis?

20. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which model will have the narrowest confidence bounds? B. Fixed effects model D. Regression ModelC. Random effects model A. Bayes model

21. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. Regression ModelC. Random effects model B. Fixed effects model A. Bayes model Which model will have the narrowest confidence bounds?

22. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html B. Fixed effects model C. Random effects model Which model will have the narrowest confidence bounds?

23. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which model will have the narrowest confidence bounds? B. Fixed effects model

24. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html Which is not a type of heterogeneity? D. ITT vs per protocol analyses B. Study quality C. The file drawer problem A. Patient subgroups

25. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. ITT vs per protocol analyses B. Study qualityA. Patient subgroups C. The file drawer problem Which is not a type of heterogeneity?

26. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html D. ITT vs per protocol analyses C. The file drawer problem Which is not a type of heterogeneity?

27. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html C. The file drawer problem Which is not a type of heterogeneity?

28. Adapted from Cochran, J.J., “Who Wants To Be A Millionaire: The Classroom Edition” INFORMS Transactions on Education, Vol. 1, No. 3, http://ite.informs.org/Vol1No3/Cochran/cochran.html THANKS FOR PLAYING!