1. Helena Chui, M.D. McCarron Professor and Chair of Neurology Director, Alzheimer Disease Research Center

2. Collaborative Research Centers Ischemic Vascular Dementia Program Project Ischemic Vascular Dementia Program Project –National Institute on Aging P01-AG12435 –Funded 1994; Now year 12 –PI: Helena Chui –Collaborators: USC, UCD, UCSF, UCLA Alzheimer Disease Research Center Alzheimer Disease Research Center –National Institute on Aging –Funded 1984; Now year 22 –PI: Yr 1-20 Caleb Finch, Ph.D.; Year 21-25 Helena Chui, M.D. –Collaborators: Gerontology, Neurology, Preventive Medicine, Pathology, Psychology, Biomedical Engineering

3. Leadership True leaders are not those who strive to be first, True leaders are not those who strive to be first, But those who are first to strive and who give their all for the success of the team. But those who are first to strive and who give their all for the success of the team. True leaders are first to see the need, envision the plan, and empower the team for action. True leaders are first to see the need, envision the plan, and empower the team for action. By the strength of the leader’s commitment, the power of the team is unleashed. By the strength of the leader’s commitment, the power of the team is unleashed.

4. Transferable Lessons Committed leadership Committed leadership –To the cause –To the team Finding one’s niche: The intersection between Finding one’s niche: The intersection between –Societal need –One’s own passion & competencies –Seizing opportunities –Navigating threats Envisioning the plan Envisioning the plan –Assembling the right players –Finding the resources –Fitting the plan to the resources Empowering the team Empowering the team –Creating win-win situations –Creating trust –Resolving conflicts –Keeping the team fit

5. Department of Neurology Mission Statement To reduce the burden of neurological disorders on humankind, through research, education, and patient care.

6. Societal Need: Highly Prevalent Neurological Disorders Alzheimer disease – 4 million Alzheimer disease – 4 million Stroke survivors – 4 million Stroke survivors – 4 million Epilepsy – 2.3 million Epilepsy – 2.3 million Parkinson disease – 1 million Parkinson disease – 1 million Multiple Sclerosis – 400,000 Multiple Sclerosis – 400,000

7. Vision for USC Neurology: Center of Excellence for Translational Research Collaborative teams of basic and clinical investigators who can bridge advances in science and technology to new & effective treatment. With special focus on neural degeneration and neural repair

8. BenchBedsidePractice Building Blocks Pathways Molecular Libraries Bioinformatics Computational Biology Translational Research Initiatives Clinical Research Informatics Integrated Research Networks Clinical outcomes Training NIH Clinical Research Associates Interdisciplinary Research Innovator Award Nanomedicine Public Private Partnerships NIH ROADMAP Biomedical Engineering Regenerative Medicine Pharmacy Repair, Recovery, Rehabilitation

9. Neurorehabilitation Partnerships USC Rancho Los Amigos National Rehabilitation Center Neurology Biokinesiology and Physical Therapy Occupational Science and Occupational Therapy Rancho New Co Physician Group Foundation Gerontology Biomedical Engineering Regenerative Medicine