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Potential Applications of Embryonic Stem Cells to Biotechnology and Medicine
Developmental biologist James Thomson in his Primate Research Center lab with a computer image of stem cell neurons at right. Photo by: Jeff Miller Date: 4/99
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Embryonic stem (ES) cells are potentially immortal cell lines that can grow in an undifferentiated state, but still retain the ability to give rise to precursor cells to all of the different human cell types.
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Fertilized egg Cleavage----> Morula (16 cells) Blastocyst about 4 days after fertilization My reference and source of pictures:
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Trophoblast Inner Cell Mass In the mouse, at least 3, but in any case, very few of the inner mass cells go on to form the embryo.
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Three Germ Layers Endoderm: tongue, tonsils, lining of lungs, digestive tract, urethra, bladder. Mesoderm: muscles, bone, lymphatic tissue, spleen, blood cells, heart, lungs, reproductive and excretory systems. Ectoderm: skin, nails, lens of eye, lining of nose, sinuses, pituitary glands, mammary glands, all parts of the nervous system.
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Scientific and Medical Benefits
Source of cells and tissue that could be used for transplantation Research tool for understanding the complex events that occur during normal human development Use to develop and test new drugs
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Legal Issues Federal law currently prohibits government funding of human embryo research.
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