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Biochemistry
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Matter Anything that has mass and takes up space
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Atoms basic building blocks of matter that make up everyday objects –90 naturally occurring kinds of atoms –Scientists have been able to make about 25 more
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Element Made of only 1 type of atom
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Elements to Know Carbon (C) Hydrogen (H) Oxygen (O) Nitrogen (N) Phosphorous (P)
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Compounds 2 or more types of atoms combined in a fixed ratio H 2 O: Water CO 2 : Carbon Dioxide
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Water Polar molecule: molecule with regions of + and – charges Cohesion: attraction between molecules of the same substance Adhesion: attraction between molecules of 2 different substances –Capillary action Solid ice is less dense than liquid water
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Organic vs. Inorganic Compounds Organic Compounds: contain carbon –Almost always contains hydrogen –Usually contain oxygen and nitrogen Inorganic Compounds: do not contain carbon –Exceptions Carbon dioxide Calcium carbonate
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Macromolecules Large molecules formed by joining smaller molecules together Biological Macromolecules are arranged in 4 categories –(1) Carbohydrates –(2) Lipids –(3) Proteins –(4) Nucleic Acids
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Polymers Molecules made from repeating units of monomers (small molecule) Monomer Polymer
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Monomers Polymers
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1. Carbohydrates Store energy and provide structural support Contain carbon, hydrogen, and oxygen Formula (CH 2 O) n –n indicates # of units in the chain
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Carbohydrates Sugars (end in –ose) –Monosaccharides: 1 sugar –Disaccharides: 2 sugars –Polysaccharides: many sugars
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Storage of Sugars organisms store excess sugar in polysaccharides –Starch: plants –Glycogen: animal
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Structure Cellulose: cell wall in plants Chitin: shells of insects
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How are disaccharides and polysaccharides made from monosaccharides? Dehydration Synthesis: Putting together Removing water
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How are polysaccharides and disaccharides broken back down into monosaccharides? Hydrolysis: add water to break bond
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2. Lipids Fats, oils, waxes Contain carbon, hydrogen, and oxygen Part of cell structures and serve as back up energy supply
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Fat structure Glycerol + 3 fatty acids (combined by dehydration synthesis) hydrophillic hydrophobic
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Saturated vs. Unsaturated Fats Saturated: all single Carbon to Carbon bonds (straight chain) Unsaturated: one or more double bonds (bent chain) oils butter
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3. Proteins Contain carbon, hydrogen, oxygen, and nitrogen –Can contain sulfur and phosphorous Cell communication, enzymes, structure, antibodies
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Amino Acid Carboxyl group Amino group
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20 Amino Acids
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Protein Structure Amino acids bonded together by dehydration synthesis
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Peptide Bond Bond which forms between amino group of one amino acid and carboxyl group of another amino acid
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Dipeptide: 2 amino acids bonded together Polypeptide: long chain of amino acids
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4. Nucleic Acids Contain carbon, hydrogen, oxygen, phosphorous, and nitrogen Include DNA and RNA Hereditary material protein synthesis
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DNA Deoxyribonucleic acid Long chain of repeating nucleotides –5 carbon sugar (deoxyribose), phosphate group, nitrogen base Double helix 2 strands
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RNA Ribonucleic acid 5 carbon sugar (ribose), phosphate group, nitrogen base One Strand
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Deoxyribose vs. Ribose
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Macromolecule (Polymer) Building Block (Monomer) CarbohydrateMonosaccharides (sugars) LipidsFatty Acids ProteinsAmino Acids Nucleic AcidNucleotides
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