1. Chem 3550 Chapter 16: Production of NADH and NADPH: The Citric Acid Cycle, the Glyoxylate Cycle (Skip), and the Pentose Phosphate Pathway

2. New Test Policy Effective 10/30/06 I will drop your lowest exam (not including the final), but only if you take all of the exams -- no exceptions Since some have access to old exams, I will post all copies of old exams (not including final) Thanks for your feedback and concerns that have been voiced My goal is to be fair and consistent -- no one gets special treatment.

3. These are all very important! Know names and cofactors, as well as reactants and products.

4. Rearrange to facilitate later oxidation (cannot oxidize 3 ° carbon) 4 Carbons 6 Carbons Loss of CO 2 Oxidation of alcohol to ketone (note use of NAD + ) 5 Carbons Similar to PDC reactions for Acetyl- CoA formation High Energy Compound GTP (or ATP) production Oxidation of alkane to alkene (note use of FAD); Succ. Deh. Is a membrane- bound enzyme Hydration Reaction is stereospecific Oxidation of alcohol to ketone (note use of NAD + ) 4 Carbons

5. This is something you should be very comfortable with

6. Know this! Regulation is very important!

7. Summary

8. Also known as E 1 Second level of control of PDC in eukaryotes Kinase: enzyme to puts on a phosphate Phosphatase: enzyme that takes of a phosphate

9. Amphibolic nature of CAC X

11. Pentose Phosphate Pathway NADPH produced! Used for lipid biosynthesis