1. n=1.831n=3.739n=3.374n=15.904n=13.297n=2.081 BP stratification according with 2003 ESH/ESC guidelines in Italian hypertensive patients included in population and clinical surveys Volpe M, et al. J Hypertension 2007;25(7):1491-8

2. n=9.382 (17.8%) n=23.172 (44.0%) n=20.161 (38.2%) n=9.382 (17.8%) n=23.172 (44.0%) n=20.161 (38.2%) Systolic BP levels (mmHg)Diastolic BP levels (mmHg) 80 83 86 89 92 95 98 Department Internal Medicine/Cardiology Hypertension Centers General Practitioners 140 143 146 149 152 155 158 Department Internal Medicine/Cardiology Hypertension Centers General Practitioners Baseline BP levels according in Italian hypertensive patients included in population and clinical surveys Volpe M, et al. J Hypertension 2007;25(7):1491-8

3. Multiple Independent Risk Factors Management (Silo Approach) Integrated Identification and management of Risk Factors contributing to CVD Risk (Global Approach) Hypertension Hypercholesterolemia Diabetes Traditional CVD Perspective New CVD Risk Perspective New CVD Risk Perspective age sex smoking Diabetes Mellitus Hyper Choleste rolemia Organ Damage Hypertension New Targets and Goals for Therapy New Targets and Goals for Therapy Reduction of Total CVD Risk Volpe M, et al. J Human Hypertens 2007; in press Modern Strategy for CVD Prevention Integrated Guidelines for Global CV Reduction