1. BIO 344 Lecture 2

2. Figure 10-11a Molecular Biology of the Cell (© Garland Science 2008)

3. Formation of sphere is energetically favorable

4. Figure 10-9a Molecular Biology of the Cell (© Garland Science 2008)

5. Figure 10-9b Molecular Biology of the Cell (© Garland Science 2008)

6. Figure 10-11b Molecular Biology of the Cell (© Garland Science 2008)

7. Figure 10-11 Molecular Biology of the Cell (© Garland Science 2008)

8. Figure 10-12 Molecular Biology of the Cell (© Garland Science 2008) Effect of cis double bonds on membranes

9. Figure 10-13 Molecular Biology of the Cell (© Garland Science 2008) 1:1 phosphotidylcholine and sphingomyelin 1:1:1 phosphotidylcholine and sphingomyelin and cholesterol

10. Figure 10-14b Molecular Biology of the Cell (© Garland Science 2008)

11. Figure 10-14a Molecular Biology of the Cell (© Garland Science 2008)

12. DVD clip 36 6,7

13. http://www.studiodaily.com/main/t echnique/tprojects/6850.html

14. Cholesterol 9

17. Cholesterol in lipid bilayer

18. DVD Clip 37

19. 10

20. Lipid composition varies among different cell types 11

21. Distribution of phospholipids and glycolipids in the lipid bilayer of human red blood cells

22. Some glycolipid molecules

23. Membrane Proteins

26. Secondary structure of protein

27. Amino acids with hydrophobic side chains

28. Hydrophobic amino acids in green and yellow

29. Predicting transmembrane helices from the amino acid sequence

31. Fraction of proteins (20 %) that span membranes

32. Secondary structure of protein

33. Examples of β-barrels

35. Detergent Micelle in Water

37. DVD clip 38

38. Structures of Two Commonly Used Detergents

39. Liposome for studying membrane properties

42. Right side out vs. inside out depends on ionic conditions used during experiment

43. Distribution of phospholipids and glycolipids in the lipid bilayer of human red blood cells

44. Membrane Proteins in Human Red Blood Cells

45. Most Membrane Proteins have Structural Functions

47. Freeze Fracture Electron Microscopy

49. Band 3 can be seen as intramembrane particles, more on P face than E face

52. DVD clip 41