1. April 20, 2006Copyright © 2006, Vedo Medico1

2. April 20, 2006Copyright © 2006, Vedo Medico2 Edema Measurement System (EMS) Presented by Vedo Medico team Ali Khan Sepehr Mogharei Arthur Arash Papian Gorji Babak Shafiei Branko Zdravkovic

3. April 20, 2006Copyright © 2006, Vedo Medico3 Agenda Introduction Purpose Product Overview Product Design Results and Analysis Challenges Timeline and Budget Conclusion Questions Demonstration

4. April 20, 2006Copyright © 2006, Vedo Medico4 Introduction Vedo Medico’s Vision –“Our business is life itself” Team: –Ali Khan – Embedded Software –Sepehr Mogharei – Hardware –Arthur Papian-Gorji – Communication –Babak Shafiei – User Interface Design –Branko Zdravkovic – Host Software

5. April 20, 2006Copyright © 2006, Vedo Medico5 Purpose Problem: –Swelling in limbs could be a sign of heart failure, kidney failure or other serious medical conditions Current Solutions: –Costly, Unreliable, Bulky, Slow –Circumference measurements Our Solution: –Edema Measurement System (EMS) –Volume measurements Leg-O-Meters Pero-System

6. April 20, 2006Copyright © 2006, Vedo Medico6 Product Overview What is Edema Measurement System (EMS) ? –Highly accurate and cost-effective device –Simple, user-friendly device that measures patient’s limb volume –Provides connectivity with PC for further measurement analysis –Portable design

7. April 20, 2006Copyright © 2006, Vedo Medico7 Product Overview Design Approaches –Digital image processing –Digital measuring using position sensors –Circumference measurement by resistance Final Design –Volume measurement by pressure sensor

8. April 20, 2006Copyright © 2006, Vedo Medico8 Product Overview

9. April 20, 2006Copyright © 2006, Vedo Medico9 Product Overview..\intr.swf

10. April 20, 2006Copyright © 2006, Vedo Medico10 Product Overview

11. April 20, 2006Copyright © 2006, Vedo Medico11 Product Design - Hardware Microprocessor: Atmel ATMega169 Sensor: Freescale® Pressure Sensor Air Pump Circuitry (Voltage Regulator, Switches) Air Bladder

12. April 20, 2006Copyright © 2006, Vedo Medico12 Product Overview EMS Control Unit –Processing component EMS Inflation Unit –Airflow control EMS Enclosure System –Air Bladder Cuff PC Diagnostic System –Database and Host Software (GUI)

13. April 20, 2006Copyright © 2006, Vedo Medico13 Product Overview

14. April 20, 2006Copyright © 2006, Vedo Medico14 Final Design X i = Base Line pressure X f = Final Pressure Volume of Leg = Volume of Enclosure – Volume of Bladder (V B ) Volume of Leg = Constant – V R V B = nrt/(pressure of the bladder) PV = nrt  V  x*(V R ) - C V  Pressure In the bladder  Linear relation

15. April 20, 2006Copyright © 2006, Vedo Medico15 Final Design..\intr2.swf

16. April 20, 2006Copyright © 2006, Vedo Medico16 Product Design – Overview

17. April 20, 2006Copyright © 2006, Vedo Medico17 Results & Analysis Preliminary Experiments –Sealed Bottles (Fixed Volume) –Linear Relationship –Added water for more volumes

18. April 20, 2006Copyright © 2006, Vedo Medico18 Results & Analysis Enclosure Experiments –Objects with known volume in place of leg –Problems Flex when pressurized Does not compress as leg does –Experimented with Measurement Parameters

19. April 20, 2006Copyright © 2006, Vedo Medico19 Results & Analysis Measurement Unit –Vedo (1 Vedo  50mL) –Volume vs. Circumference –Test objects range from 10 to 37 Vedo Repeatability –Same measurement done many times –Standard deviations of ~1 Vedo

20. April 20, 2006Copyright © 2006, Vedo Medico20 Product Design - Software Embedded Software –3 Menu: Simple Operation Host Software –GUI: Visual Basic Program –MS Access Database

21. April 20, 2006Copyright © 2006, Vedo Medico21 Product Design - Software Start View Data Connect PC Save Measurement Patient Name Patient Measurements Measuring…. Enter Patient Name New Patient Syncing…. Host Software

22. April 20, 2006Copyright © 2006, Vedo Medico22 Product Design - Software User friendly GUI

23. April 20, 2006Copyright © 2006, Vedo Medico23 Product Design - Software Clearly presenting data

24. April 20, 2006Copyright © 2006, Vedo Medico24 Product Design - Software Designing a fully functional DB 2 tier application, support many users

25. April 20, 2006Copyright © 2006, Vedo Medico25 Product Design - Software Synchronization and handshaking Plug and Play behavior Handling exceptions in the DB Communication between application & DB DB queries optimization

26. April 20, 2006Copyright © 2006, Vedo Medico26 Challenges - Software AVR DataFlash® –Stopped functioning Program Memory Limitation –Required Embedded Software Optimization

27. April 20, 2006Copyright © 2006, Vedo Medico27 Challenges - Hardware Pressure Sensor –Too sensitive Enclosure System –Initial Bladder too small –Sealed food saver bags

28. April 20, 2006Copyright © 2006, Vedo Medico28 Future Work Integrate device with blood pressure monitor Make DataFlash® operational Wireless connectivity to PC Redesign the Enclosure to be soft and flexible

29. April 20, 2006Copyright © 2006, Vedo Medico29 Timeline Task Actual timelineAchieved timeline Project proposalJanuary 23 rd ResearchFebruary 15 th February 10 th Functional SpecsFebruary 20 th Design SpecsMarch 6 th March 9 th Enclosure DesignMarch 6 th February 15 th Preliminary HardwareMarch 10 th March 15 th Embedded SoftwareApril 15 th April 10 th IntegrationApril 10 th April 16 th Fully functional PrototypeApril 10 th April 20 th

30. April 20, 2006Copyright © 2006, Vedo Medico30 Budget Projected CostActual Cost Microcontroller/Debugger Software $40.00$65 Sensors$150.00$62.75 Actuator( Pump/Valve)$80.00$134.72 Serial Interface$50N/A Power supply / Battery$100.00N/A Enclosure$20.00$82.75 Prototype Board$30.00N/A Electronic components$15.00$52.94 Shipping & Handling$25.00$14.00 Total$510.00$412.16

31. April 20, 2006Copyright © 2006, Vedo Medico31 Conclusion Air Pressure sensor and Properties of ideal gases. Challenging experience starting project from scratch to completion Try to keep the solution simple. (Less implementation time, less error). Order extra parts for key components

32. April 20, 2006Copyright © 2006, Vedo Medico32 Acknowledgements Dr. Andrew Rawicz Dr. Tatjana Z. Dr. Hamid Masoodi Fairchild Semiconductors FreeScale

33. April 20, 2006Copyright © 2006, Vedo Medico33 Questions?