1. OEB 192 – 09.10.19 Tradeoffs, specialization & pleiotropy

2. (Cooper et al., 2003) (Chou et al., 2009)

3. (Travisano & Lenski, 1995)

5. http://iarnuocon.newsvine.com/_news/2008/06/24/1605998-lenski-schools-conservapedia-on-science http://rationalwiki.com/wiki/Lenski_affair

9. (Bennett & Lenski, 2007)

10. (Lee et al., 2009)

11. Wednesday (10/21): Mutation rate & population size I.

12. Tomorrow: OEB Special Seminar: “Symbioses and Early Prokaryotic Evolution” James A. Lake Department of Molecular, Cell and Developmental Biology Department of Human Genetics University of California, Los Angeles Tuesday, October 20, 2009 at 4:00 p.m. Biological Laboratories Main Lecture Hall, Room 1068 16 Divinity Avenue HOST: Hartl Lab Abstract: Endosymbioses have dramatically altered eukaryotic life, but are thought to have negligibly affected prokaryotic evolution. By analyzing the flows of protein families, evidence is presented indicating that the double membrane, Gram negative, prokaryotes were formed as the result of a symbiosis between an ancient actinobacterium and clostridium. This extraordinarily successful taxon has profoundly altered the evolution of life by providing endosymbionts necessary for the emergence of eukaryotes and by generating Earth’s oxygen atmosphere. Their double membrane architecture and the observed genome flows into them suggest a common evolutionary mechanism for their origin: an endosymbiosis between a clostridium and actinobacterium.

13. The Max Tishler Prize Lectures 2009 October 26 John Sutherland, University of Manchester RNA: Prebiotic Product or Biotic Invention? Part 1 Pfizer Lecture Hall from 4:00 pm to 5:00 pm October 27 John Sutherland, University of Manchester RNA: Prebiotic Product or Biotic Invention? Part II Pfizer Lecture Hall from 4:00 pm to 5:00 pm