1. Energy, Catalysis and Biosynthesis Metabolism *catabolism *anabolism Complexity of metabolism Review of Energy: Energy *kinetic energy *potential energy

2. Free energy, stability, work capacity and change Free energy Change in free energy =  G Gravitational Motion DiffusionChemical Reaction

3. Free energy, stability, work capacity and change Equilibrium *chemical equilibrium  G = 0, no net change in the system Chemical reactions with free energy changes: *energetically favorable*energetically unfavorable

4. Metabolic Disequilibrium *Multistep open hydroelectric system

5. Enzymes Enzymes speed up metabolic reactions:

6. Enzymes Enzymes are catalytic proteins Enzymes lower the barrier of E A

7. Enzymes Induced Fit

8. Enzymes: How they work

9. Enzymes Physical and chemical properties affect enzyme activity: *inhibitor *cofactor *coenzyme *activators

10. ATP Main types of (cellular) work: *mechanical *transport *chemical

12. ATP