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Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.01 Tumors in human liver.

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Presentation on theme: "Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.01 Tumors in human liver."— Presentation transcript:

1 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.01 Tumors in human liver.

2 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.02 Action of proto-oncogenes and tumor suppressor genes.

3 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.03a Contact inhibition.

4 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.03b Contact inhibition.

5 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Page 561a.

6 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Page 561b.

7 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.04 the mismatch repair protein MutS bound to DNA.

8 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.05 Base-excision repair.

9 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.06a Glycosylase binding to oxoG.

10 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.06b Glycosylase binding to oxoG.

11 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.07a The uracil-DNA glycosylase reaction.

12 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.07b The uracil-DNA glycosylase reaction.

13 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.08 The AP endonuclease reaction.

14 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figrue 18.09 Nucleotide excision repair.

15 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.10 Xeroderma pigmentosum.

16 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.11 Recombination to bypass a single-strand gap.

17 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.12 Homolgous recombination to replicate past a double-strand break.

18 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.13 End joining of broken DNA.

19 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.14 Model of a RecA-DNA complex.

20 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.15 The cell cycle and cyclin activity.

21 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.16 Model of DNA damage response pathway.

22 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.17 Action of the retinoblastoma protein.

23 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.18 Partial structure of the BRCA 1 protein.

24 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.19a Structure of the core domain of P53.

25 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure 18.19b Structure of the core domain of P53.


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