1. Trifunctional Aminoamide Cellulose Derivative and its Characterization

2. Outline Objectives Problem statement and motivation of the study Presuppositions from Literature Methodology

3. Objectives To illustrate how to use a couple of techniques to confirm the structural of a newly synthesized material and its intermediate. To illustrate how to use a couple of techniques to characterize a final product and so provide some information for applications.

4. Problem statement and motivation of the study What are dendrimers? “A dendrimer is a molecule with a form like the branches of a tree.”[1] Dendrimers can be used in pharmaceutics, genetics, catalyst chemistry and superconductor currently or potentially. [2] [1] Wikipedia [2] Sand, Anders. Dendrimers and Their Technical Applicability

5. Cellulose-based dendrimers Zhang, Changde et al. Biomacromolecules (2006), 7(1), 139-145.

6. Presuppositions from Literature Narrow molecular weight distribution The most exciting physical property of dendrimers is the variation of their intrinsic viscosities with molecular weight. [6] It is found that, when the generation increases beyond a certain point, the intrinsic viscosity begins to decline, contrary to the behavior of linear polymers (Fig.4). [6] http://www.dendritech.com/pamam.htmlhttp://www.dendritech.com/pamam.html

7. Methodology Using 1H to confirm the structural of intermediate product: Using FT-IR to confirm and characterize the structural of CMCBA and CMCBADMPDA: Using NMR to confirm and characterize the structural of CMCBA and CMCBADMPDA: Using TGA to Characterize the Degree of Substitution of CMCBA and CMCBADMPDA: Using Intrinsic Viscosity to characterize the conformation of CMCBADMPDA: Using GPC-LS to characterize the MW and MWD of CMCBADMPDA:

8. Using 1H to confirm the structural of intermediate product:

9. Using FT-IR to confirm and characterize the structural

10. Using NMR to confirm and characterize the structural of CMCBA and CMCBADMPDA:

11. Using TGA to Characterize the Degree of Substitution

12. Using Intrinsic Viscosity to characterize the conformation CMC 5.62 dL/g, CMCDMPDA 3.57 dL/g CMCBADMPDA 0.39 dL/g

13. Using GPC-LS to characterize the MW and MWD of CMCBADMPDA:

14. Conclusions The author got the “right ” product. The product is of very low viscosity, which is suitable for drug delivery.