1. Do Now:

2. DNA Fingerprinting Everyone (except identical twins) has a unique DNA sequence in their cells. A technique called ________________________can be used to ________________________(or parents) using their DNA. DNA fingerprinting is MUCH more accurate than traditional fingerprints

3. How DNA Fingerprinting Works DNA is extracted from a sample (like when you got DNA from strawberries) Special enzymes called _________________________ are used to cut the DNA samples into pieces. The DNA pieces are then put through a process called _____________________________

4. Gel electrophoresis Gel electrophoresis is used to _________________ _________________. DNA molecules are separated by ____________.

5. Analyzing the Results The gel shown shows what happened when the same piece of DNA was cut up with 3 different enzymes. Standard Sizes DNA fragment Restriction Enzymes

6. Solving Crimes: Rape investigation The DNA from a rapist can be collected from the victim for up to about 24 hours after the crime. The DNA found can then be compared to the DNA of suspects. Which suspect committed the crime?

7. DNA Fingerprint Paternity Testing DNA fingerprinting (with gel electrophoresis) can be used to determine who the __________ of an organism are. Just like genes, DNA fragments are _____________ from both parents

8. Final Thoughts A DNA fingerprint is like a unique _______________ for every organism on Earth. DNA fingerprinting can be used to __________________________and determine who an individual’s genetic __________________ are. DNA fingerprinting uses ________________________to separate different size pieces of DNA created by chopping up the original piece using special enzymes

9. mRNA Processing Remember the central dogma of molecular biology: _______  _________  ___________ In __________________, there is one more little step in between RNA and protein. After an mRNA is made by transcription, it must be __________________ before _________________.

10. Introns & Exons An mRNA sequence has ___________ and __________ within it. Before being used to make proteins, the introns must be ___________________. Intron: A part of an mRNA molecule that ____________________________ before translation. Exon: A part of an mRNA molecule that will be _______________________________.

11. Get rid of those Introns! Before introns are removed, an RNA molecule is called ________________________________________ Only the ______________ make it to translation!

12. That’s it for Molecular Genetics Your review guide is due tomorrow! We will be playing Jeopardy tomorrow: your review guide will be the only notes you may use. Use the remainder of the period (and tonight) to complete anything on the review guide you haven’t yet.