1. EMT 296 Medical Presentations Blaze Amodei

2. Rhabdomyolysis is the rapid breakdown of skeletal muscle tissue due to injury to muscle tissue. skeletal muscle

3.  Trauma  Obstruction of blood  Excessive muscle strain or activity  Electrical

4.  Disorders of muscle energy supply (usually hereditary enzyme problems)  Poisons  Drugs of abuse  Medications  Autoimmune muscle damage  Electrolyte and metabolic disturbances Electrolyte  Infections

5.  Pain, tenderness or numbness  Weakness  Edema  Signs of shock  Compartment syndrome  Facial damage (blood vessels and nerves)  Nausea and vomiting  Confusion  Coma  Arrhythmias  Abnormal urine production  Disseminated intravascular coagulation

6.  Mechanism of injury and nature of illness  The most reliable test in the diagnosis of rhabdomyolysis is the level of creatine kinase (CK) in the blood.creatine kinase

8.  Cell damage  Impairing the blood supple  Metabolic interference  Further cell damage  Inflammatory response  Fascial compartment  Renal failure

9. “Chlorophyll? More like BOREophyll.”

10.  Fluid therapy Treat for shock and preserve kidney function Normal saline (6-12 L recommended in 24 hours) Drugs?  Electrolytes Why and why not…  Treat the patient!

11. QUESTIONS?

12. Wikimedia Foundation, IncWikimedia Foundation, Inc.“Rhabdomyolysis” [online] last modified on 21 May 2008, at 20:23. http://en.wikipedia.org/wiki/Rhabdomyolysishttp://en.wikipedia.org/wiki/Rhabdomyolysis Emedicine. “Rhabdomyolysis”. Sandy Craig, MD [Online] last modified on Nov 30, 2006. http://www.emedicine.com/EMERG/topic508.htmhttp://www.emedicine.com/EMERG/topic508.htm Mayo Clinic. “Rhabdomyolysis: What are the symptoms?” [online] Last modified on Aug 16, 2006. Gerald Gau, M.D. http://www.mayoclinic.com/health/rhabdomyolysis/AN01413Gerald Gau, M.D http://www.mayoclinic.com/health/rhabdomyolysis/AN01413 Rhabdomyolysis organization. “Rhabdomyolysis Kidney Failure and Damage” [online] copyright 2007. http://www.rhabdomyolysis.org/http://www.rhabdomyolysis.org/