1. BMES Conference: Student Technology Transfer Brian Mullen, Ph.D

2. Confidential Overview Introduction to Therapeutic Systems –Why we started –Pain & Solution –Where we are now Starting up as a Student: –Navigating the “Bermuda Triangle” Timeline and development overview mentors & entrepreneurship programs Lessons Learned

3. Confidential Compelled to Act

4. Confidential Autism Spectrum Disorders 1 in 110 people 10-17% annual growth $35 billion societal cost annually ‒ 27 States have Mandated Autism coverage

5. Confidential Personal, Portable, Deep Pressure –Provides personalized deep touch pressure to anyone, anywhere, at any time. –Marketing Campaign: Brand, Social Networking, Website –Launched: 4/1/11

6. Confidential Accomplishments to Date Licensed & Filed Patents Board of Directors Scientific Advisory Board World class Manufacturing Partner FDA Registered Class 1 Exempted Device Brand & Identity Raised Capital April Launch –Initial Sales KOL’s Including –Autism Speaks –Easter Seals –Dr. Temple Grandin Support

7. Confidential CVIP, COI, CEO, Ph.D 7 University Business Student Tech Transfer

8. Confidential Timeline 2004 – Fall: started grad school & research project 2006 –Fall: started exploring commercialization 2008 –Spring: won BP competition & NCIIA grant –Fall: Conflict of Interest process 2009 –Summer: Defended 2010 –Winter: Obtained License 8

9. Confidential Integrated Design & Development Customers Driven by Clinical Data & Research Foundations Design GMP & Quality Regulatory Reimbursement Manufacturing Marketing & Brand KOLs Clinical Data

10. Confidential Mentors & Relationships PhD & Master’s committee/ mentors for the academics “Business committee”/ mentors for the company Relationships are your the most important & most valuable asset. Student/ committee chair relationship is the most important 10

11. Confidential Entrepreneurship programs Encouragement Knowledge Critical Validation Resources & Support –Mentors –Capital Capital: ~$80k –Grants, Awards, Fellowships Mentors –Chair of our board, lead investor Seed Round Investors 11

12. Confidential Programs NCIIA Grinspoon Foundation Entrepreneurship Club UMass Business Plan Competition Isenberg Fellow Business Classes Amherst Center for Entrepreneurship Accelerator MassChallenge 12

13. Confidential Lessons Learned & Suggestions IT IS A LONG TERM RELATIONSHIP…a Marriage –pick your battles Understand the other person’s side –Ie Laws that have to be followed by the university. –Room for flexibility & opportunity –Understand the impact to the facility /students MOST IMPORTANT: the student is not a faculty member.

14. Confidential Lessons Learned & Suggestions Student should always be evaluating what they want and letting people know. –Student has to be made aware of the decisions and implications Do your homework –Read and know the university policies. –ask a lot of questions. –Get good mentors. 14