2. What is the role of free PSA?

4. Total PSA Range 2.5 to 4.0 ng/ml Age Range (Years) %Free PSA<60 (yrs)>=60 (yrs)All Ages <7849591 7-15254943 16-25102722 >25276 Total PSA Range 2.5 to 4.0 ng/ml Age Range (Years)

5. Total PSA Range 4.01 to 10.0 ng/ml Age Range (Years) %Free PSA<60 (yrs)>=60 (yrs)All Ages <7879593 7-15275048 16-251227 >25377

6. Total PSA Range10.01 to 20.0 ng/ml Age Range (Years) %Free PSA<60 (yrs)>=60 (yrs)All Ages <79397 7-15437167 16-25224745 >25515 Total PSA Range10.01 to 20.0 ng/ml Age Range (Years)

7. Table 1 - Suggested upper limits of PSA for different age groups ² Age (years)Serum PSA (ng/ml) 40 - 49 50 - 59 60 - 69 70 - 79 2.0 3.0 4.0 5.5

8. Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial

9. Cancer Screening Trial (PLCO)

10. ERSPC)