1. Psoriasis: The New Skin Paris Fears Queens University of Charlotte SPAEP I Pittsburgh, PA

2. Psoriasis ‘Psora’ means to itch in Greek Gain an understanding of the disease, Psoriasis Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions Table of Contents

3. Psoriasis Psoriasis, a chronic non- infectious immune-mediated inflammatory skin condition that causes thick red and flaky patches of skin Natural Course 5 common types Questions Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

4. Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

5. Psoriasis Psoriasis, a chronic non- infectious immune-mediated imflammatory skin condition that causes thick red and flaky patches of skin Natural Course 5 common type Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents Plaque*-basic dry, itchy, red skin in common sites Guttate- proceeds after strep throat; numerous red scaly bumps Inverse*- occurs in excess skin folds and soft tissue Pustular- small pus filled bumps on whole body or hands and feet Erythrodermic- aggressive plaque with pain and wide patches on entire body

6. Psoriasis Mistoken for 150 years 1700’s to 1800’s Robert Willian and Jacob Plenck 1841 Ferdinand von Hebra Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

7. Psoriasis 7.5-8.5 million 125 million 150,000 400 Everyone is at risk Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

8. Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents 40% increase in risk of contracting Psoriasis with "familial tendency" Identical Twins incidence

9. Psoriasis Psoriasis triggers Stress Little Sun Light Injury to skin Medication Immune system deficiencies Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

10. Psoriasis Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

11. Psoriasis Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

12. Psoriasis $1.6 billion to $4.3 billion dollars 75% believe in negative impact Comorbidities HIV CVD Obesity and Alcohol Abuse Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

13. Psoriasis Controlled not Cured Topical treatments Home remedies Pills Alternative treatments Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

14. Summary Prevalent in all genders races, and ages 3-95 Effects about 125 million people worldwide Complex auto-immune inflammatory skin condition which includes, white scaly and raised red lesions Triggers include anything from bacterial and viral infection to stress The exact schematics to cure this disease are still a mystery Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

15. QUESTIONS? Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents

16. Introduction What is Psoriasis Background Epidemiology Genetics Physiology Quality of Life Treatments Conclusion Questions References Table of Contents References Babu, Hanish. "History of Psoriasis.” General Medicine (suite 101) (2008): n. pag. Web. 17 Jul 2011. http://www.suite101.com/content/history-of-psoriasis-a85546. http://www.suite101.com/content/history-of-psoriasis-a85546 Bhosle, Monali J, Amit Kulkarni, Steven R Feldman, and Rajesh Balkrishnan. "Quality of life in patients with psoriasis." Health and Quality of Life Outcomes 4.35 (2006): Web. 17 Jul 2011. http://www.hqlo.com/content/4/1/35>.http://www.hqlo.com/content/4/1/35 Kurian, Anil, and Benjamin Barankin. "Current Effective Topical Therapies in the Management of Psoriasis." Skin Therapy Letter 16.1 (2011): 4-7. Web. 26 Jun 2011.http://www.skintherapyletter.com/2011/16.1/2.html.http://www.skintherapyletter.com/2011/16.1/2.html Schön, Michael P, and W.-Henning Boehncke. "Psoriasis." N Engl J Med 352. (2005): n. pag. Web. 17 Jul 2011. http://www.nejm.org/doi/full/10.1056/NEJMra041320#t=article. http://www.nejm.org/doi/full/10.1056/NEJMra041320#t=article