1. Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002

2. DNA

3. Transcription

4. Translation Notion of “gene expression”

5. Question: Why aren’t “identical twins” identical?

6. Epigenetics From Wikipedia: “Epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence.” http://www.pbs.org/wgbh/nova/body/epigenetics.html Is epigenetics why cloned animals don’t fare well?

7. Genetic regulation

8. Genetic Switches (in “non-expressed” regions)

9. Genetic Regulatory Networks

10. Random Boolean Networks as models of genetic regulatory networks