1. Hazardous Materials

2. Chemical Inventory Each Laboratory must maintain a complete, accurate and up to date chemical inventory. Each Laboratory must maintain a complete, accurate and up to date chemical inventory. The inventory should include: The inventory should include: –All Chemicals  Hazardous  Non-hazardous –Compressed Gasses

3. Chemical Inventory When you are doing the inventory, it is a good time to discard any chemicals that: When you are doing the inventory, it is a good time to discard any chemicals that: –Have expired. –Are no longer being used. –Have containers that have been compromised, i.e. cracked lid. –Have labels that are illegible. Submit your updated inventory to Submit your updated inventory to EH&S on a yearly basis. EH&S on a yearly basis.

4. Safety Data Sheets - SDS A Safety Data Sheet or SDS is information provided by the manufacturer and maintained by the employer to inform employees of the possible hazards associated with chemicals being used in their work area. It is part of a hazard communication program. A Safety Data Sheet or SDS is information provided by the manufacturer and maintained by the employer to inform employees of the possible hazards associated with chemicals being used in their work area. It is part of a hazard communication program.

5. Safety Data Sheets - SDS As stated in 29 CFR 1910.1200(g)(8), “the employer (Lab) shall maintain in the workplace copies of the required SDS…and shall ensure that they are readily accessible during each work shift to employees when they are in their work area.” safety data sheets for each hazardous chemical This can be done by: As stated in 29 CFR 1910.1200(g)(8), “the employer (Lab) shall maintain in the workplace copies of the required SDS…and shall ensure that they are readily accessible during each work shift to employees when they are in their work area.” safety data sheets for each hazardous chemical This can be done by: –Shared database in which all laboratory workers have access. workers have access. –Stored hardcopies that are sent from the manufacturer.

6. Safety Data Sheets - SDS Each Laboratory must maintain a current SDS for each chemical or compound being stored or used in the laboratory. Each Laboratory must maintain a current SDS for each chemical or compound being stored or used in the laboratory. SDS location must be clearly marked. SDS location must be clearly marked. Each laboratory worker needs to use and understand SDS’s. Each laboratory worker needs to use and understand SDS’s.

7. Global Harmonization Standard (GHS) The revised Hazard Communication Program incorporates the GHS and refers to MSDS as Safety Data Sheets (SDS). The revised Hazard Communication Program incorporates the GHS and refers to MSDS as Safety Data Sheets (SDS). It also requires that the information on the SDS is presented using consistent headings in a specified sequence. It also requires that the information on the SDS is presented using consistent headings in a specified sequence.

8. SDS Format Section 1: Identification of the substance or mixture and of the supplier. Section 1: Identification of the substance or mixture and of the supplier. –Consists of a product identifier, supplier or manufacture details, recommendations and restrictions of use, and an emergency telephone number. Section 2: Hazards identification Section 2: Hazards identification –Consists of the GHS classification of the substance and/or mixture, as well as any national or local information. GHS label elements, such as symbols, precautionary statements and other hazards which are not covered by the GHS, can also be provided in this section.

9. Section 3: Composition/Information on ingredients Section 3: Composition/Information on ingredients –Contains the chemical identity, common name and synonyms of the given substance and/or mixture. The chemical identity and concentration of all hazardous ingredients will be provided for all hazardous mixtures. –CAS numbers, EC numbers, impurities and stabilizing additives should also be provided in this section as well. Section 4: First aid measures Section 4: First aid measures –Consists of descriptions for necessary measures that are subdivided according to the most important symptoms/effects from different routes of exposure, such as, inhalation, skin and eye contact and ingestion.

10. Section 5: Firefighting measures Section 5: Firefighting measures –Suitable extinguishing media and special protective equipment and precautions for firefighters, as well as any specific hazards arising from the chemical. Section 6: Accidental release measures Section 6: Accidental release measures –Includes personal precautions, protective equipment and emergency procedures. Environmental precautions, methods and materials for containment and cleaning up are available in this section as well. Section 7: Handling and storage Section 7: Handling and storage –Contains precautions for safe handling and conditions for safe storage, including any incompatibilities with other chemicals.

11. Section 8: Exposure controls/personal protection Section 8: Exposure controls/personal protection –Includes control parameters, such as, occupational exposure limits or biological limits. Appropriate engineering controls and individual protection measures, such as protective equipment is provided in this section as well. Section 9: Physical and chemical properties Section 9: Physical and chemical properties –Contains the physical and chemical properties, such as, appearance, odor, pH level, melting point/freezing point and flash point, etc.

12. Section 10: Stability and reactivity Section 10: Stability and reactivity –Contains information on the chemical stability and possible hazardous reactions. Section 11: Toxicological information Section 11: Toxicological information –A description of various health effects and the information one needs to know in order to identify the side effects. Section 12: Ecological information (not required) Section 12: Ecological information (not required) –Includes any adverse effects on the environment such as Eco toxicity and degradability.

13. Section 13: Disposal considerations (Not Required) Section 13: Disposal considerations (Not Required) –Includes a description of waste remains and information on safe disposal. Section 14: Transport information (Not Required) Section 14: Transport information (Not Required) –Contains information such as the UN number, shipping name and the transport hazard class or classes. Section 15: Regulatory information (Not Required) Section 15: Regulatory information (Not Required) –Consists of any specific regulations for the identified product. Section 16: Other information Section 16: Other information –Contains any other information, such as preparation date and revision of the SDS.

14. SDS Emergency In an emergency and you cannot retrieve an SDS, one can be obtained by calling the 3E Company’s 24 Hour phone #: 800-451-8346Or760-602-8703

15. Chemical Storage Separate incompatible chemicals. Separate incompatible chemicals. –Separate oxidizers from organics –Separate flammable liquids, acids and bases Provide earthquake restraints for all shelving when storing chemicals or glassware. Provide earthquake restraints for all shelving when storing chemicals or glassware. Secondary containment needs to be provide if there is a risk of release Secondary containment needs to be provide if there is a risk of release into the environment. into the environment.

16. Chemical Storage Storage container MUST be compatible with material. Storage container MUST be compatible with material. –Example: Metal containers cannot be used for acids and bases. Food containers MUST NEVER BE USED for chemical storage. Food containers MUST NEVER BE USED for chemical storage.

17. Weekly Inspection At least weekly, the Responsible Party must inspect areas used for hazardous materials storage. At least weekly, the Responsible Party must inspect areas used for hazardous materials storage. You must look for leaking containers, for deterioration of containers and for deterioration of the containment system. You must look for leaking containers, for deterioration of containers and for deterioration of the containment system. Any issues found must be corrected immediately. Any issues found must be corrected immediately.

18. Weekly Inspection A written record of this weekly inspection should be posted in the laboratory or work area. A written record of this weekly inspection should be posted in the laboratory or work area. You can make your own sheet or contact your EH&S inspector for one. You can make your own sheet or contact your EH&S inspector for one.

19. Flammable Liquids Storage If a lab has quantities greater than 10 gallons, they must be stored in an approved flammable liquids storage cabinet. If a lab has quantities greater than 10 gallons, they must be stored in an approved flammable liquids storage cabinet. Containers that can be shattered or punctured easily must be in secondary containment. Containers that can be shattered or punctured easily must be in secondary containment. Do not store with acids or bases. Do not store with acids or bases.

20. Acids Storage Store in secondary containment Store in secondary containment Cannot be stored at or above eye level. Cannot be stored at or above eye level. Label cabinets “Acid” with 3” letters Label cabinets “Acid” with 3” letters Store by acid class in separate secondary containment Store by acid class in separate secondary containment –Organic –Inorganic –Oxidizing

21. Common Organic Acids Glacial Acetic Acid Glacial Acetic Acid Trichloroacetic Acid Trichloroacetic Acid Trifluoroacetic Acid Trifluoroacetic Acid Formic Acid Formic Acid Citric Acid Citric Acid Benzoic Acid Benzoic Acid Butyric Acid Butyric Acid Propionic Acid Propionic Acid

22. Common Inorganic Acids Hydrochloric Acid Hydrochloric Acid Hydrofluoric Acid Hydrofluoric Acid Hydrobromic Acid Hydrobromic Acid Phosphoric Acid Phosphoric Acid Chromic Acid Chromic Acid

23. Common Oxidizing Acids Nitric Acid Nitric Acid Perchloric Acid Perchloric Acid Sulfuric Acid Sulfuric Acid

24. Bases Storage Store in secondary containment Store in secondary containment Store away from acids and solvents Store away from acids and solvents Cannot be stored at or above eye level. Cannot be stored at or above eye level. Label cabinets “Base” with 3” letters Label cabinets “Base” with 3” letters Examples: Examples: –Hydroxides –Amines –Ammonia –Bleach

25. Compressed Gasses Must be upright and restrained Must be upright and restrained –At least two chains must fit snuggly around the cylinders. Separate incompatible gasses Separate incompatible gasses –Flammable & Oxidizing by 20 feet Keep caps on while in transportation or storage Keep caps on while in transportation or storage

26. Peroxide Formers Peroxide formers must be dated when received, opened and when checked for peroxides. Peroxide formers must be dated when received, opened and when checked for peroxides. Test for peroxides annually and label with the tested ppm level. Test for peroxides annually and label with the tested ppm level. Any container that is suspected of peroxide formation or tests at a level above 25 ppm should be given to EH&S for disposal. Any container that is suspected of peroxide formation or tests at a level above 25 ppm should be given to EH&S for disposal. Prudent practices are to use or dispose of peroxides within 2 years of opening. Prudent practices are to use or dispose of peroxides within 2 years of opening. List of Peroxide formers can be found at: http://bfa.sdsu.edu/ehs/pdf/ClassPeroxidizableChem.pdf List of Peroxide formers can be found at: http://bfa.sdsu.edu/ehs/pdf/ClassPeroxidizableChem.pdf

27. Chemical Labeling All containers in the laboratory must be properly labeled with the name of the material being stored in the container. This includes non-hazardous materials such as: All containers in the laboratory must be properly labeled with the name of the material being stored in the container. This includes non-hazardous materials such as: –Water –Weak buffers –Salts Full name with NO abbreviations. Full name with NO abbreviations.

28. Containers must also include the physical and health hazards of the material. Containers must also include the physical and health hazards of the material. Chemical Labeling No Hazard!

29. Physical Hazards Flammable Flammable Pyrophoric Pyrophoric Self-Heating Self-Heating Self-Reactive Self-Reactive Compressed Gas Compressed Gas Explosive Explosive Oxidizer Oxidizer Organic Peroxide Organic Peroxide Corrosive Corrosive

30. Carcinogen Carcinogen Mutagenicity Mutagenicity Reproductive Toxin Reproductive Toxin Respiratory Sensitizer Respiratory Sensitizer Target Organ Toxin Target Organ Toxin Aspiration Toxin Aspiration Toxin Toxic/Acute Toxin Toxic/Acute Toxin Irritant Irritant Skin Sensitizer Skin Sensitizer Eye Damage Eye Damage Narcotic Effects Narcotic Effects Respiratory Tract Irritant Respiratory Tract Irritant Burns skin Burns skin Health Hazards

31. Labeling Information Consult the SDS or the manufacturer’s label for accurate labeling information. Consult the SDS or the manufacturer’s label for accurate labeling information.

32. Global Harmonization System (GHS) The GHS uses globally recognized categories and pictograms for manufactures to communicate hazards on chemicals bottles.

34. Hazard pictograms are one of the key elements for the labeling of containers under the GHS, along with: An identification of the product; An identification of the product; A signal word – either DANGER or WARNING – where necessary A signal word – either DANGER or WARNING – where necessary Hazard Statements, indicating the nature and degree of the risks posed by the product Hazard Statements, indicating the nature and degree of the risks posed by the product Precautionary Statements, indicating how the product should be handled to minimize risks to the user (as well as to other people and the general environment) Precautionary Statements, indicating how the product should be handled to minimize risks to the user (as well as to other people and the general environment) The identity of the supplier The identity of the supplier (who might be a manufacturer (who might be a manufacturer or importer) or importer) Global Harmonization System

35. HMIS “Hazardous Materials Identification System” for Secondary Containers The HMIS rating is a color-coded, alphanumeric system which gives information about the health, flammability and reactivity of the chemical in question. The system rates a material from a minimal hazard through a serious hazard. It also recommends the appropriate personal protective equipment to be worn when handling the particular chemical.

36. Example of HMIS

37. HMIS Health 0 - Minimal Hazard 0 - Minimal Hazard Not significant risk to health. Not significant risk to health. 1 - Slight Hazard 1 - Slight Hazard Irritation or minor reversible injury possible. Irritation or minor reversible injury possible. 2 - Moderate Hazard 2 - Moderate Hazard Temporary or minor injury may occur. Temporary or minor injury may occur. 3 - Serious Hazard 3 - Serious Hazard Major injury likely unless prompt action is taken and medical treatment is given. Major injury likely unless prompt action is taken and medical treatment is given. 4 - Severe Hazard 4 - Severe Hazard Life-threatening, major or permanent damage may result from single or repeated over exposures. Life-threatening, major or permanent damage may result from single or repeated over exposures.

38. HMIS Flammability 0 - Minimal Hazard 0 - Minimal Hazard Materials that will not burn. Usually includes any material that will not burn in air when exposed to a temperature of 1500°F. for a period of 5 minutes Materials that will not burn. Usually includes any material that will not burn in air when exposed to a temperature of 1500°F. for a period of 5 minutes 1 - Slight Hazard 1 - Slight Hazard Materials that must be preheated before ignition can occur. Materials that must be preheated before ignition can occur. 2 - Moderate Hazard 2 - Moderate Hazard Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. 3 - Serious Hazard 3 - Serious Hazard Materials capable of ignition under almost all ambient temperature conditions. Materials capable of ignition under almost all ambient temperature conditions. 4 - Severe Hazard 4 - Severe Hazard Materials that will rapidly or completely vaporize at atmospheric pressure and Materials that will rapidly or completely vaporize at atmospheric pressure and normal ambient temperatures with a flashpoint below 73°F. Materials may ignite normal ambient temperatures with a flashpoint below 73°F. Materials may ignite spontaneously with air. spontaneously with air.

39. HMIS Reactivity 0 - Minimal Hazard 0 - Minimal Hazard Materials that are normally stable even under fire conditions. Materials that are normally stable even under fire conditions. 1 - Slight Hazard 1 - Slight Hazard Materials that are normally stable but that can become unstable at elevated temperatures and pressures. Materials that are normally stable but that can become unstable at elevated temperatures and pressures. 2 - Moderate Hazard 2 - Moderate Hazard Materials that readily undergo violent chemical change at elevated temperatures and pressures. These materials may also react violently with water. Materials that readily undergo violent chemical change at elevated temperatures and pressures. These materials may also react violently with water. 3 - Serious Hazard 3 - Serious Hazard Materials that are capable of detonation or explosive decomposition but require a strong initiating source or materials the react explosively with water. Materials that are capable of detonation or explosive decomposition but require a strong initiating source or materials the react explosively with water. 4 - Severe Hazard 4 - Severe Hazard Materials that are readily capable of detonation or explosive decomposition or Materials that are readily capable of detonation or explosive decomposition or explosive reaction at normal temperatures and pressures. explosive reaction at normal temperatures and pressures.

40. HMIS Protective Equipment

41. San Diego State University 5500 Campanile Drive San Diego, CA 92182 Other Hazmat Labeling- Sample 3 0 1 x x x x x Ethanol

42. This labeling is not adequate.

43. Exposure Routes of Exposure Inhalation Inhalation Absorption Absorption Ingestion Ingestion Injection Injection

44. Exposure Control Prevent exposures to hazardous materials. Prevent exposures to hazardous materials. –Inhalation – Keep containers closed, use the fume hood, reduce volumes. –Absorption – Wear gloves, lab coat, safety glasses, clean up spills promptly. –Ingestion – Don’t eat, drink, smoke or apply cosmetics in the laboratory. Don’t store hazardous material in food containers. –Injection – Use care when handling sharps. Properly dispose of sharps. sharps. Properly dispose of sharps.

45. Exposure Control Engineering controls: Engineering controls: -hoods, cabinets, safety cans, trays Work practices: Work practices: -Standard operating procedures Personal protective equipment: Personal protective equipment: - safety glasses, lab coats, gloves, no open-toed shoes

46. Be Safe, Act Responsibly, Accidents Really Do Happen

47. Types of Emergencies Medical emergency Medical emergency –Immediately call 911 Fire Fire Chemical spill Chemical spill Biohazardous material spill Biohazardous material spill

48. Emergency Response If an emergency occurs, notify: If an emergency occurs, notify: –Notify the supervisor or anyone in your area your safety officer or EH&S (x46778). If after business hours, notify Public Safety (911). If after business hours, notify Public Safety (911).

49. Remember, to review at any time Consult the Hazardous Materials and Hazardous Waste Management Practices Booklet provided by EH&S. Consult the Hazardous Materials and Hazardous Waste Management Practices Booklet provided by EH&S.

50. Frequently Asked Questions Q. How do I know what is the appropriate Personal Protective Equipment (PPE) that I should wear? Q. How do I know what is the appropriate Personal Protective Equipment (PPE) that I should wear? A. Check the SDS for the material or sometimes the manufacture’s label will have the information. SDS’s are also a great tool in deciding how to label your containers. A. Check the SDS for the material or sometimes the manufacture’s label will have the information. SDS’s are also a great tool in deciding how to label your containers.

51. Frequently Asked Questions Q. I can’t fit all the required information on my container because it is too small. What can I do? Q. I can’t fit all the required information on my container because it is too small. What can I do? A. Difficult question. Labeling the contents of the container is priority. If that is all the information you can fit on it, place the container into secondary containment like a beaker and write all the additional information on the secondary containment. A. Difficult question. Labeling the contents of the container is priority. If that is all the information you can fit on it, place the container into secondary containment like a beaker and write all the additional information on the secondary containment.

52. Frequently Asked Questions Q. Do I need to use the blue, red, yellow and white HMIS labels? Q. Do I need to use the blue, red, yellow and white HMIS labels? No, it would be ideal if everyone did but sometimes it not practical. You can use whatever method you can. Be it masking tape or sharpies. As long as all the information is there, it is legible and stays on the container, you are fine. No, it would be ideal if everyone did but sometimes it not practical. You can use whatever method you can. Be it masking tape or sharpies. As long as all the information is there, it is legible and stays on the container, you are fine.

53. Frequently Asked Questions Q. Why do I need to label something has just plain water in it? Q. Why do I need to label something has just plain water in it? A. A container with water looks just like a container with Hydrochloric Acid or any other clear liquid. You can’t tell if something is dangerous just by looking at it. That is the purpose of Hazard Communication. Communicate what is hazardous and what is not. A. A container with water looks just like a container with Hydrochloric Acid or any other clear liquid. You can’t tell if something is dangerous just by looking at it. That is the purpose of Hazard Communication. Communicate what is hazardous and what is not.

54. The End