1. QAH HospitalPortsmouth Hospitals NHS Trust6/9/2015Page 1 Academic support for researchers at Portsmouth Hospitals Trust

2. QAH HospitalPortsmouth Hospitals NHS TrustPage 26/9/2015Page 2 Examples of targets from PHT research strategy 2009-2014 :  Increase departments/specialities engaging in research  Increase participation across all professional groups  Increase Patient Public Involvement  Identify, target and support Trust staff and Clinical Departments with the skills and capabilities to secure external funding from recognised NIHR portfolio partners.  Utilise the expertise and support of key partners in creating opportunities and driving performance.  Translate local basic science expertise into clinical research opportunities and outcomes for the Trust.  Work closely with academic partners to create opportunities for new clinical academic posts and research fellowships.

3. QAH HospitalPortsmouth Hospitals NHS TrustPage 36/9/2015Page 3 Anne Davis Sophie Coles Lina Chong Jonathan Nash Martin Wise Emma Munro Sue Atkins Richard Aspinall Alison Charig Rebecca Hardcastle Mike Holubinka Shady Zeidan Susan McCormack Ellis Goatley Tom Brown Serena Cottrell Matt Turner

4. QAH HospitalPortsmouth Hospitals NHS TrustPage 46/9/2015Page 4 Challenges….  Time limitations within clinical roles  Balancing clinical priorities and academic aspirations  Few joint clinical-academic appointments to facilitate collaboration  Short rotations of junior support staff  Limited intra and inter-departmental forums to discuss and progress research ideas  Focus on recruitment to hosted studies  Lack of small funding pots for start-up or pilot studies  Need for academic support

5. QAH HospitalPortsmouth Hospitals NHS TrustPage 56/9/2015Page 5 Challenges….  Time limitations within clinical roles  Balancing clinical priorities and academic aspirations  Few joint clinical-academic appointments to facilitate collaboration  Short rotations of junior support staff  Limited intra and inter-departmental forums to discuss and progress research ideas  Focus on recruitment to hosted studies  Lack of small funding pots for start-up or pilot studies  Need for academic support

6. QAH HospitalPortsmouth Hospitals NHS TrustPage 66/9/2015Page 6 If a man tries to break open a coconut with his head, he will not live to eat that coconut Yoruba proverb

7. QAH HospitalPortsmouth Hospitals NHS TrustPage 76/9/2015Page 7 NIHR Research Design Service (South Central) Faculty of Science, University of Portsmouth (School of Health Sciences and Social Work, Institute of Biomedical and Biological Sciences) Research nurse protocol development group PHT library services Research facilitator one- to-one and project management Other academic / industry collaborative links Researcher Pack Head of nursing, AHP and midwifery research Research Quality Committee Research Medical Officer posts Accurate costings Public Patient Involvement

8. QAH HospitalPortsmouth Hospitals NHS TrustPage 86/9/2015Page 8 Develop study Additional site NHS permission Research Idea Study Concept & Feasibility Ethics & regulatory approval NHS permission Initial sponsor Assessment evaluation Meet RDS & decide level of support Provisional R&D Sponsorship Apply for Permission at R&D host sites Study set up Consult R&D website Book and meet with R&D Submit for R&D review Consult & agree Support services Full R&D Sponsorship/ Research Quality Committee Populate/revise IRAS dataset & Register Trial Transfer to R&D for review & signature Populate/revise IRAS R&D & SSI form Transfer to R&D for review & signature REC, Regulatory & NHS permissions Contact Potential PI at Host site Define Study type at host site Host NHS site Approval study initiation meeting Study planning with R&D and support services Trial/site Master File in place study start Apply for Funding/ Peer review Submit REC, PAF & MHRA applications Transfer SSI & study docs for review & signature Confirm readiness MS1MS2MS3MS4 MS5

9. QAH HospitalPortsmouth Hospitals NHS TrustPage 96/9/2015Page 9  Funded by NIHR to provide free advice, to assist researchers who are developing proposals for national peer-reviewed funding competitions for applied health or social care research  Methodological support (clinical trials, quantitative, qualitative)  Statistical advice  Health economics expertise  Team building and collaborations  Public patient involvement  Pre-submission review panels  Ethics advice  Information on training events and masterclasses www.rds-sc.nihr.ac.uk

10. QAH HospitalPortsmouth Hospitals NHS TrustPage 106/9/2015Page 10  Evidence-based rationale for research question  Development of study objectives  Tailoring of study design to objectives, consideration of mixed-methods  Advice on feasibility/pilot studies  Review of appropriate outcome measures  Strategies for recruitment  Avoiding bias in the study design  Key data points and data collection methods  Logistical considerations  Ethical considerations  Calculation of sample size  Methods of data analysis  Dissemination plan Methodological support

11. QAH HospitalPortsmouth Hospitals NHS TrustPage 116/9/2015Page 11 Researcher pack  Detailed protocol template and top tips  Governance information  List of key research and methodological references  List of funding websites  Courses available (e.g. systematic reviews, qualitative, statistics)  Patient journey and costings  Information on study set-up and management  Integrated Research Application System information (aka ‘ethics’)  Example project management templates  Standard Operating Procedure guidance  Local educational courses information.........and much much more!

12. QAH HospitalPortsmouth Hospitals NHS TrustPage 126/9/2015Page 12 Patient Public Involvement  Recent NCRN ‘mystery shopper’ report revealed low proportion of patients aware of research activities in Trusts throughout England  Quality Improvement Awards Bid to and increase patient recruitment into studies enable patients to influence development of new studies originating at PHT  includes: –PPI Officer –Information/communication focus –Establish links with condition-specific and community groups –Participant Research Experience Survey –PPI reference group –Develop PHT PPI in research strategy

13. QAH HospitalPortsmouth Hospitals NHS TrustPage 136/9/2015Page 13 PHT Staff on Clinical academic pathways (Nurses, midwives, Allied Health Professionals – through Greta Westwood - g.westwood@soton.ac.uk)  40% clinical, 60% academic  4 year programme  NHS funded  £14,000 Stipend 2012: 4 doctoral fellows – 3 nurses, 1 occupational therapist (endoscopy, ITU, paediatrics, MAU); 5 internships (SHA funded), 1 nurse consultant – breast cancer care 2013: 7 fellows – 3 nurses from Medicine for older people, 4 midwives. Opening of PHT Clinical Academic Unit.

14. QAH HospitalPortsmouth Hospitals NHS Trust The LASER Trial (Temperature Controlled Laminar Airflow in Severe Asthma for Exacerbation Reduction Portsmouth Hospitals NHS Trust Coordinating Centre Oxford Respiratory Clinical Trials Unit University Hospital Southampton NHS Foundation Trust University Hospitals of Leicester NHS Trust RDS South Central PHT R&D Department (Sponsor) Centre for Statistics in Medicine Health Economics Research Centre University of Portsmouth Patient Public Involvement: Wessex Severe Asthma Cohort ENGAGE (Portsmouth Uni lay member research group) Asthma UK/British Lung Foundation Airsonett (Industry) HIOW CLRN A recent example – The LASER trial

15. QAH HospitalPortsmouth Hospitals NHS TrustPage 156/9/2015Page 15 What we would like to see in the future  More PHT-originated projects seeking funding and portfolio status (more researchers, more grants)  Research seminar series  Departmental research meetings  PHT staff doing research degrees (clinical academic pathways at Soton, MD / MRes at University of Portsmouth)  Formalised departmental programmes of work and research strategies  Increased peer / interdepartmental support/mentoring  Development of common data management strategies  More ‘outputs’ – publications, intellectual property What else would YOU like?

16. QAH HospitalPortsmouth Hospitals NHS TrustPage 166/9/2015Page 16

17. QAH HospitalPortsmouth Hospitals NHS Trust Serena Cottrell Page 176/9/2015Page 17 YOUR PICTURE HERE!! Anne Davis Sophie Coles Lina Chong Jonathan Nash Martin Wise Emma Munro Sue Atkins Richard Aspinall Alison Charig Rebecca Hardcastle Mike Holubinka Shady Zeidan Susan McCormack Ellis Goatley Tom Brown Matt Turner

18. QAH HospitalPortsmouth Hospitals NHS TrustPage 186/9/2015Page 18 Thank you……….. ….and hope to see you soon! Carole.Fogg@port.ac.uk researchoffice@porthosp.nhs.uk www.rds-sc.nihr.ac.uk