1. Psychopharmacology [Instructor name] [Class name section number]

2. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

3. Introduction Psychoactive Drugs  Communication between neurons Neurotransmitter Activity  Agonists – increase  Antagonists – decrease Side Effects

4. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

5. Pharmacokinetics Drug effects in the body  Absorption  Distribution  Metabolism  Excretion

6. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

7. Drug Administration Absorption  Slowest: Oral  Fastest: Intravenous/Inhalation Rapid Absorption = high abuse potential

8. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

9. Drug Metabolism  Liver enzymes  Repeated exposure  Tolerance  Enzyme induction  Dangers of grapefruit juice

10. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

11. Treatment Approaches Pharmacology + Therapy = Most Effective Medication can be problematic due to individual variations.

12. Discussion What is the best treatment for depression?depression

13. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

14. Juveniles and Psychopharmacology  High prevalence  Difficult to prescribe and research  Increase in diagnoses

15. The Elderly and Psychopharmacology  Rapidly aging population  Polypharmacy  Risks

16. Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

17. SSRIs, Suicidality, Violence, and Mania  Why doesn’t everyone just take a “happy pill”?  Serious side-effects  What are other barriers to drug therapies?

18. Medication Adherence Easy as can be… right? Diagnosis: HIV Treatment: Kool-Aid packets/tic-tac mints Must adhere to the assigned treatment protocol What will make treatment easier/harder?

19. Photo Attribution Slide 1 Photo Credit: Seth Anderson http://www.flickr.com/photos/44124372363@N01/7752724816 https://creativecommons.org/licenses/by-sa/2.0/ Slide 5 Photo Credit: anitacanita https://www.flickr.com/photos/86508273@N00/631386556/ https://creativecommons.org/licenses/by-nc-nd/2.0/ Slide 9Photo Credit: Eme. http://pixabay.com/en/grapefruit-rose-sour-fruit-343615/ Slide 11 Photo Credit: Barack Obama https://www.flickr.com/photos/94975828@N00/6774968388/ https://creativecommons.org/licenses/by-nc-sa/2.0/ Slide 11 Photo Credit: torbakhopper HE DEAD https://www.flickr.com/photos/gazeronly/129649817/ https://creativecommons.org/licenses/by/2.0/ Slide 11 Photo Credit: Jobopa https://www.flickr.com/photos/43904604@N06/13041631074/ https://creativecommons.org/licenses/by-nc-nd/2.0/ Slide 11 Photo Credit: Otabi kitahachi https://www.flickr.com/photos/otabi/3947682278/ https://creativecommons.org/licenses/by-nc-sa/2.0/ Slide 11 Photo Credit: paolovalde https://www.flickr.com/photos/35034358028@N01/2581632664/ https://creativecommons.org/licenses/by-nc-nd/2.0/ Slide 11 Photo Credit: liber https://www.flickr.com/photos/51035655291@N01/200858281/ https://creativecommons.org/licenses/by-sa/2.0/ Slide 12 Photo Credit: Alan Cleaver https://www.flickr.com/photos/11121568@N06/4102645583/ https://creativecommons.org/licenses/by/2.0/ Slide 14 Photo Credit: Rosie O'Beirne http://www.flickr.com/photos/rosieobeirne/4090200924/ https://creativecommons.org/licenses/by-nc-nd/2.0/ Slide 15 Photo Credit: WarzauWynn https://www.flickr.com/photos/94246031@N00/4416203874/ https://creativecommons.org/licenses/by-nc/2.0/ Slide 17 Phot Credit: Sharon Drummond http://www.flickr.com/photos/28085418@N07/5159112853 https://creativecommons.org/licenses/by-nc-sa/2.0/ Slide 18 Photo Credit: Auntie P https://www.flickr.com/photos/32625013@N00/3177877243/ https://creativecommons.org/licenses/by-nc-sa/2.0/