1. Phone:313.577.1200 Fax:313.993.4079 www.oehs.wayne.edu

2. Laws affecting Laboratories n OSHA Laboratory Standard n OSHA Bloodborne Pathogen Standard n Substance - specific standards

3. n Scope and Application: Applies to laboratories “workplace where relatively small quantities of chemicals are used on non-production basis” Employers are required to: n Monitor exposures to regulated hazardous chemicals n Provide Information and Training n Prepare, implement and maintain a written Chemical Hygiene Plan (CHP) n Provide Personal Protective Equipment (PPE) n Hazard Identification n Provide for medical consultations\exams n Recordkeeping OSHA Occupational Exposures to Hazardous Chemicals in Laboratories Standard (29CFR1910.1450)

4. Chemical Hygiene Plan n What is a Chemical Hygiene Plan? WSU’s policy for the OSHA Lab Std. n Copy should be available in lab also at www.oehs.wayne.edu n Why is important to you? Contains information on your safety and rights.

5. Generic Standard Operating Procedures (common sense do’s and don’ts) n Developed by OEH&S n Included in the Chemical Hygiene Plan n Examples: –Chemical storage –Using compressed gases –Emergency response

6. Specific Standard Operating Procedures n Lab staff write them: Specific to experiments n No required format n Required content: –hazard controls –personal protective equipment –health & safety information –decontamination, waste disposal, etc. n Template available at OEHS website

7. Working with Compounds of Unknown Toxicity These are chemicals for which there are no known statistically significant studies to establish toxicity n use a designated work area n isolate items used there n decontaminate when work is completed n use local exhaust ventilation n use appropriate PPE n wash hands often

8. Where to find information on Chemical Hazards Where do you look to find information on new chemicals BEFORE you use them? n Merck Index n Aldrich Catalog n Prudent Practices in the Laboratory n Sax’s Dangerous Properties of Industrial Materials n Material Safety Data Sheet (MSDS)

9. Material Safety Data Sheets MSDSs n MSDS provide you with: –Chemical and physical properties –Health and physical hazards –Toxicity information –Compatibility/Incompatibility –Spill and fire response –Personal protective equipment And much more...

10. How do I get a MSDS? n OEH&S maintains complete database n Manufacturer sends MSDSs to OEH&S - they will usually send you one if requested n Manufacturer’s Web Site n Various Health & Safety Web Sites n If you receive a MSDS for a chemical in your lab, you must keep it on file.

11. Control Measures n Protective Equipment n Safety Equipment –safety showers, eyewashes, fire extinguishers, first aid kits, explosion- proof refrigerators n Lab Maintenance and Inspection –safety inspections, fumehood condition, chemical storage, good housekeeping

12. What’s wrong here?

13. Keep the fumehood sash in the proper place – at the yellow arrow.

14. Chemical Fume Hoods: Protect you from chemical exposures!

15. n Set sash at correct height n Wear PPE n Work towards middle of hood n Keep hood uncluttered Chemical Fume Hood Use

16. n It’s important not to block air flow in the fume hood. n Large equipment placed in a fume hood, should be on blocks or racks to allow air flow under the equipment. Chemical Fume Hood Use

17. n Excess storage and clutter may affect the performance of the hood and increase the risk of spills and other accidents.

18. Biological safety cabinets protect you and your research. They should be certified annually by OEH&S.

19. Safety Equipment n Showers checked by bldg. Engineer n Flush eyewashes weekly

20. n Access to emergency equipment is essential. n Check to ensure that equipment is not blocked.

21. Fire Extinguishers n Know where fire extinguishers are located in your lab. –are extinguishers in proper location? –have they been discharged/damaged? n Extinguishers are checked by Office of Risk Management: 7-3110 n Replaced or repaired by FP&M: 7-4315

22. Personal Protective Equipment (PPE) Is it appropriate for work you are doing? n Gloves n Eye Protection n Labcoats, aprons, scrubs n No shorts or open-toed shoes

23. Gloves n select gloves appropriate for the task n check gloves for leaks n double glove if necessary n be alert to unusual sensations in hands n do not touch your face, telephone, etc with contaminated gloves n remove gloves before leaving lab

24. Wear lab coat, gloves, eye protection when working with chemicals! n Remove your gloves and WASH YOUR HANDS before leaving the laboratory.

25. Glass cuts are the #1 injury reported in labs.

26. Safety Glasses “must be worn in any area where there is the potential for eye injury” n Eye protection used must be ANSI approved (“Z87” stamped on the sidebar) n Must be appropriate for the hazard n If prescription glasses are not ANSI approved, you must wear safety glasses, safety goggles or a full face shield over them

28. No eating, drinking, etc… in labs

29. No eating/drinking in labs n Areas outside of the lab must be designated for food and drinks to be stored and eaten.

30. Signs & Labels Custom Lab Signs available from OEH&S

31. Label Chemical Storage Areas according to the hazard!

32. n Lab Standard does not specify labeling language, but, all lab employees must know what the label means and be able to refer to the appropriate MSDS. n Rules for hazardous waste labeling are more restrictive… as you’ll learn later on. Chemical Labels

33. n All chemicals, even bottles of water, must be labeled!

34. Keep labels intact!

35. Secure cylinders properly… this isn’t the right way!

36. These are properly secured cylinders

37. n Liquid chemicals should be stored by class: –flammables –organic acids –mineral acids –bases –oxidizers –carcinogens/highly toxic reagents n Where storage space is limited, separation using plastic tubs is acceptable. Chemical Storage

38. Separate Incompatible Chemicals! n Acids: away from bases, flammable solvents, oxidizers n Cyanides: separate from acids n Water reactives: keep separate n Flammables with very low flashpoints: store in an explosion proof refrigerator n Peroxidizables: date when opened, dispose of when expired (ethers, tetrahydrafuran, dioxane)

39. n If total quantity of flammable liquids exceeds 10 gallons… these materials must be stored in a flammable storage cabinet.

40. n Dry chemicals may be stored alphabetically or in any convenient manner. n For all chemicals: Keep on hand only the amounts that you have room to store properly.