1. LJ-001

2.  Enveloped and Naked Viruses  Modes of Infection  LJ-001

3. Gary E. Kaiser

5.  Enveloped and Naked Viruses  Modes of Infection  LJ-001

6. Russell Kightley Media

7. Naked Naked Lytic cycle Exocytosis Enveloped Dan Stowell Botany Online Visual Resource Library

8.  Enveloped and Naked Viruses  Modes of Infection  LJ-001

9.  A small anti-viral molecule effective against enveloped (but not naked) viruses. Wolf et. al.

11.  Influenza A  Filoviruses  Poxviruses  Arenaviruses  Bunyaviruses  Paramyxoviruses  Flaviviruses  HIV-1  Hepatitis C  Ebola  And others

12.  Viruses can’t make their own proteins or repair their membrane like a cell can

14. Russell Kightley Media

15. Wolf et. al.

16.  Still very early in development, further testing needed  Shorten Viral Infection Course  Preventative Measure?  Could be put in condoms  New treatment for multiple viruses  Eliminate temporary infections  Fight Chronic ones  LJ001 is effective at very low doses  Potentially Excellent Therapeutic Index

17.  Russell Kightley Media  Virco Online  Humanitarian Futures Programme  Gary E. Kaiser  HOPES (The Huntinton’s Disease Outreach Project for Education) at Stanford  Molecular Station

18.  Wolf et. al. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. Epub 2010 Jan 28.  Balzarini J. Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy. Nat Rev Microbiol. 2007 Aug;5(8):583-97.  Kudchodkar S., Levine, B. Viruses and Autophagy. Reviews in Medical Virology. 2009; 19: 359-378  Melikyan GB. Common principles and intermediates of viral protein- mediated fusion: the HIV-1 paradigm. Retrovirology. 2008 Dec 10;5:111.

19. Xkcd.com