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Chapter 17 (Part 1) Amino Acid Metabolism: Nitrogen Assimilation and Amino Acid Biosynthesis
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Nitrogen Cycle
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Nitrogenase
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Nitrate and Nitrite to Ammonia
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Ammonia Assimilation
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Glutamate Dehydrogenase
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Glutamine Synthetase (GS)
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Glutamine back to Glutamate
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Allosteric Modulation of GS Acitivity in Bacteria
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Regulation of Bacterial GS by Covalent Modification
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Glutamate serves as primary N- donor for AA synthesis through transamination reactions
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Transamination rxns involve Pyridoxol-phosphate and formation of Schiff Base
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Essential vs. Non-Essential AA’s
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Amino Acid Biosynthesis is a Diverse Process
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