2. 1.Where on the chest wall can you hear the heartbeat the best? 2. Name this structure 3. Name this valve 4. When the ventricles are in systole, is this valve open or closed? 5. What is a heart murmur?

3. Blood Vessels Histological structure of vessels arteries maintaining constant blood pressure aneurisms capillaries veins variations in circulatory pathways examples of portal systems blood supply to the brain

4. Fig. 20.1(TE Art) Systemic circuit Pulmonary circuit CO 2 O2O2 O2O2 artery vein artery

5. Tunica intima endothelium BM Tunica media smooth muscle collagen some elastin Tunica externa loose CT vasa vasorum Tunica intima Tunica media Tunica externaL. artery Medium sized artery arteriole venule Medium sized vein L. vein capillary

7. 1. Conducting arteries expand & recoil With increasing and decreasing pressure 2. measure pressure, adjust HR and dilate or constrict BV’s High BP Lower HR How to maintain constant blood pressure

8. Fig. 21.4(TE Art) Carotid body Common carotid artery Aortic body Aortic arch Carotid sinus Baroreceptors

9. Fig. 16.1(TE Art) Glossopharyngeal Nerve (CN IX) Vagus nerve (CN X) Baroreceptors sense increased blood pressure Heart rate decreases

10. Aneurysm: weak point in an artery or heart wall common in abdominal aorta renal arteries & brain

11. Cerebral vascular accident (CVA) = stroke

12. Fig. 21.5b

13. Sphincters open Arteriole Venule Precapillary sphincters Metarteriole Sphincters closed

14. Continuous Fenestrated Sinusoids pericyte Endothelial cell hepatocyte Clefts Tight junctions Clefts Pores

15. To heart Contracted skeletal muscles Relaxed skeletal muscles Valve open Valve closed Vein

16. Fig. 21.10(TE Art) Distribution of blood Pulmonary 18% Veins 54% Systemic 70% Heart 12% Arteries 11% Capillaries 5%

17. 1 capillary bed

18. Pulmonary trunk (artery) Pulmonary vein

19. Fig. 21.12(TE Art) Portal system (2 capillary beds)

20. hypothalamus Anterior pituitary

21. pan spleen Gastric veins Superior Mesenteric V Hepatic sinusoids IVC Hepatic portal system

22. Fig. 21.12(TE Art) 1 capillary bed Portal system (2 capillary beds) Arteriovenous anastomosis Arterial anastomosesVenous anastomoses

23. Internal carotid Vertebral artery

24. Cerebrovascular Accident = CVA = stroke Internal carotid Basilar Vertebral Circle of Willis