1. Motion correction in 3D PET/CT using optical flow methods M Dawood, F Büther, N Lang, X Jiang, M Schäfers, O Schober, KP Schäfers Nuclear Medicine, University Hospital Münster, Germany

2. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Problem Spatial non-correspondance between PET and CT due to motion

3. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Optical Flow A method to estimate deformation between image frames Independent of the form and type of movement between the frames Non-rigid and pixel-based

4. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Combined Local/Global Minimize f LG

5. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Discontinuity Preserving Non-Quadratic Non-Quadratic approach allows better approximation than least squares Discontinuity preservation allows better estimation across organ boundaries Minimize f D

6. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Lukas/Kanade Horn/Schunck Bruhn Non-LinearDiscontinuity Preserving Result Demonstration

7. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Results 1 (Phantom)

8. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Results 2 ( 13 N-NH 3 )

9. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging.

10. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Results 2 ( 13 N-NH 3 )

11. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Results 3 ( 18 F-FDG)

12. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Results 3 ( 18 F-FDG)

13. Motion correction with optical flow algorithms M. Dawood et al. Motion correction in 3d pet/ct with advanced optical flow algorithms. Submitted to ieee transactions on medical imaging. Thank you!