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Co-Transporters Na + /Glucose Symport Vibrio cholerae Prokaryote Water-bourne pathogen Produces Cholera Toxin.

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Presentation on theme: "Co-Transporters Na + /Glucose Symport Vibrio cholerae Prokaryote Water-bourne pathogen Produces Cholera Toxin."— Presentation transcript:

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5 Co-Transporters

6 Na + /Glucose Symport

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8 Vibrio cholerae Prokaryote Water-bourne pathogen Produces Cholera Toxin

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13 Chloride Ion Channel (CFTR) involved in Cystic Fibrosis CFTR = Cystic Fibrosis Transmembrane conductance Regulator

14 K = Lysine R = Arginine CFTR Channel Protein

15 Healthy Lung Lung epithelial cells

16 Cystic Fibrosis Lung

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18 Misfolded CFTR protein Degraded in ER

19 CF Gene Therapy Flu virus with Normal CFTR gene

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22 Na + /K + ATP-dependent Active Transporter (Pump) Pg. 396 (see also Fig. 12-12)

23 K + “Leak” Channel

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