1. Male Reproductive Function Anatomy Hormonal Control Pathophysiology

2. Male Reproductive Function Anatomy Hormonal Control Pathophysiology

3. Testicular Anatomy

4. Spermatogenesis

5. Sertoli cell nucleus

6. Cross-section of seminiferous tubule

8. Male Reproductive Function Anatomy Hormonal Control Pathophysiology

9. Hypothalamo-pituitary-gonadal axis GnRH FSH LH Leydig cells testosterone Sertoli cells Androgen binding proteinsinhibin - ? - spermatogonia T response to 5 minute conversation 0 10 20 30 40 talking to malestalking to females % increase in T

10. Sertoli cell nucleus Leydig cells LH T FSH ABP inhibin 2  sex characteristics

11. Male Reproductive Function Anatomy Hormonal Control Pathophysiology

12. Precocious Puberty Temperature Sensitivity of Sperm Production Hypogonadism –hyperprolactinemia –Feminizing adrenocortical carcinoma –Cannabinoids –HIV Hypergonadism Gynocomastia use of anabolic steroids Environmental effects on sperm count