1. Oct.28, 2003 The 4th Kitasato-Harvard Symposium1 Investigator Initiated Trial (IIT) A View from Industries Dr.M.Iwasaki (Aventis Pharma)

2. Oct.28, 2003 The 4th Kitasato-Harvard Symposium2 New Movement Manual for IIT Prof. Ueda’s 2 nd Task Force on GCP Basis for coming MHLW Notification Notification is planned in March ’04 Educational seminar (ex, JSCO) Preparation of a IIT at NCC Several proposals to the industries

3. Oct.28, 2003 The 4th Kitasato-Harvard Symposium3 A Message from Us Fundamental support for IIT We should take this activity positively As it gives us opportunity to provide more efficient clinical trial methodology to investigators As it gives also investigators opportunity to recognize the real world of “Clinical Studies” Need to clarify issues for improvement Ready to continue collaboration

4. Oct.28, 2003 The 4th Kitasato-Harvard Symposium4 Proposals A face to face meeting with the key player for IIT Clarify uncertainties / issues Seek for the way to solve them Introduction of a process that enables us to check the scientific, ethical and administration matters of IITs For the better mutual understanding