1. Photometric Innovations for Biotechnology Who are we? EnVision Instruments Photometric Systems –Cell Density (Model CDP) –Ultra-violet Absorption (Model UVS) –Turbidity Foundation Fieldbus/Bluetooth Interfaces Advanced Optics Technologies Biotech/Pharmaceutical/Food & Beverage Industries

2. User Interface Criteria Photometric Innovations for Biotechnology Lab scale and manufacturing environments Compatible with existing and new equipment Small space requirements Keep development cost down Support requirements for HW and SW Ease-of-use

3. Bluetooth Wireless Interface Low-power 2.4 - 2.5 GHz wireless communication (10 meter range) Robust, readily available, inexpensive Fewer connectors, cables and failure points Interfaces to standard man/machine interfaces (Desktop PC, laptop, PDA) - no external custom transmitter Setup / configuration / monitoring only Industry standard 4-20 mA output provided Options: –Serial cable replacement –Web browser –Other Bluetooth “profiles”? Photometric Innovations for Biotechnology

4. Foundation Fieldbus Interface Positives Interoperable digital-only interface Adopted by biotech industry Two-wire interface with loop-power capability for low power devices Intrinsically-safe capability Availability of standard hardware and software Distributed process automation and control Fault tolerance “Smart” devices and predictive maintenance Photometric Innovations for Biotechnology

5. Foundation Fieldbus Interface Other issues Standard user layer based on “blocks” like AI, AO, PID High cost of implementation –Software communications stack and function blocks –Specialized hardware –Fieldbus Foundation approval and registration –Needs large investment or third party assistance Relatively slow data updates rates for some instruments H1 and HSE devices –H1 is 31.25 kbit –HSE is 10 Mb ethernet Photometric Innovations for Biotechnology

6. Our CDP Implementation Configuration via Bluetooth or Fieldbus –Separation of UI hardware and software –Internal modified Modbus interface Foundation Fieldbus H1 device with two AI blocks –Bus/Loop powered (45 mA rating) Bluetooth Wireless Web Server Interface –Uses a standard PC or PDA browser such as Internet Explorer or Mozilla Security and User Level Support 250 ms update rate over FF and 4-20 output Photometric Innovations for Biotechnology

9. UVS “PurSpec” Analyzer In-Line UV Spectrophotometer Larger data requirements Same UI architecture Photometric Innovations for Biotechnology