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Cell Division and Apoptosis II chapter 17
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Activation of a cyclin dependent kinase
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CdK activity can be suppressed by inhibitory phosphorylation
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CdK activity can be suppressed by inhibitory proteins
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Cell fusion experiments
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Assembly of pre-replicative complex during G1 phase
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Entry into mitosis is blocked by incomplete DNA replication Hydroxyurea blocks DNA synthesis Caffeine causes failure of checkpoint
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The Rb protein acts as a brake in mammalian cells
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Overview of cell cycle control system
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Programmed Cell Death - Apoptosis
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Digits in developing mouse paw are formed through apoptosis cells undergoing apoptosis
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Apoptosis causes tadpole to lose tail
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Necrosis vs. apoptosis
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DVD clip 77
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Procaspase is activated by an active caspase
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Caspase cascade occurs during apoptosis
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An animal cell depends on extracellular signals to survive or divide
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An animal cell depends on extracellular signals to differentiate. Without extracellular signals the cell will die
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Platelet derived growth factor was the first mitogen isolated stimulates cell division during wound healing
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Mitogens stimulate G1-Cdk and G1/S-Cdk activities
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