1. Wednesday, December 1 Factorial Design ANOVA

2. The factorial design is used to study the relationship of two or more independent variables (called factors) to a dependent variable, where each factor has two or more levels. - p. 333

3. The factorial design is used to study the relationship of two or more independent variables (called factors) to a dependent variable, where each factor has two or more levels. In this design, you can evaluate the main effects of each factor independently (essentially equivalent to doing one- way ANOVA’s for each of the factors independently), but you are also able to evaluate how the two (or more factors) interact.

4. Examples of Interaction Effects Two drugs in combination may have a negative effect – aspirin is not effective for angina if combined with ibuprofen. An educational intervention program may be more effective for one group (boys) than for another (girls).

7. TOTAL VARIATION Variation within groups (error) Variation between groups Variation from Factor 1 Variation from Factor 2 Variation from Factor 1 x 2 interaction Partitioning variation in a factorial design.

11. 1.ACompute SS T B. Compute SS B C.Subtract SS B from SS T to obtain SS W (error) D.Compute SS 1 E.Compute SS 2 F.Compute SS 1x2 by subtracting SS 1 and SS 2 from SS B 2.Convert SS to MS by dividing SS by the appropriate d.f. 3.Test MS 1,MS 2 and MS 1x2 using F ratio.

13. More advanced ANOVA topics N-way ANOVA Repeated Measures designs Mixed models Contrasts